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Tae-Ik Choi

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Articles 32
Citations 397
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Recent Articles
1.
Shin Y, Kim S, Choi T, Kim C, An W
Epigenetics Chromatin . 2024 Nov; 17(1):35. PMID: 39587626
Background: Bone remodeling is a continuous and balanced process which relies on the dynamic equilibrium between osteoclastic bone resorption and osteoblastic bone formation. During osteoclast differentiation, pro-osteoclastogenic and anti-osteoclastogenic genes...
2.
Park J, Choi T, Kim T, Lee Y, Wellalage Don D, George-Abraham J, et al.
J Genet Genomics . 2024 Oct; 51(12):1389-1403. PMID: 39368701
Williams syndrome (WS) is a rare multisystemic disorder caused by recurrent microdeletions on 7q11.23, characterized by intellectual disability, distinctive craniofacial and dental features, and cardiovascular problems. Previous studies have explored...
3.
Roychaudhury A, Lee Y, Choi T, Thomas M, Khan T, Yousaf H, et al.
Ann Neurol . 2024 Jul; 96(5):914-931. PMID: 39073169
Objective: Intellectual disability is often the outcome of neurodevelopmental disorders and is characterized by significant impairments in intellectual and adaptive functioning. X-linked intellectual disability (XLID) is a subset of these...
4.
Kim T, Roychaudhury A, Kim H, Choi T, Baek S, Thyme S, et al.
Transl Psychiatry . 2024 Feb; 14(1):82. PMID: 38331943
Genetic variants in ZNF536 contribute to the risk for neuropsychiatric disorders such as schizophrenia, autism, and others. The role of this putative transcriptional repressor in brain development and function is,...
5.
Shepherdson J, Hutchison K, Wellalage Don D, McGillivray G, Choi T, Allan C, et al.
Am J Hum Genet . 2024 Feb; 111(3):487-508. PMID: 38325380
Pathogenic variants in multiple genes on the X chromosome have been implicated in syndromic and non-syndromic intellectual disability disorders. ZFX on Xp22.11 encodes a transcription factor that has been linked...
6.
Kim H, Kim H, Jung S, Han J, Jo S, Kim I, et al.
Mar Drugs . 2023 Dec; 21(12). PMID: 38132928
The discovery of new highly effective anticancer drugs with few side effects is a challenge for drug development research. Natural or synthetic anticancer peptides (ACPs) represent a new generation of...
7.
Lee M, Han H, Choi T, Lee K, Baasankhuu A, Kim H, et al.
Front Cell Dev Biol . 2023 Jun; 11:1200599. PMID: 37363725
Ciliopathies are human genetic disorders caused by abnormal formation and dysfunction of cellular cilia. Cilia are microtubule-based organelles that project into the extracellular space and transduce molecular and chemical signals...
8.
Lee Y, Thomas M, Roychaudhury A, Skinner C, Maconachie G, Crosier M, et al.
Res Sq . 2023 Mar; PMID: 36993381
Intellectual disability (ID) is a common neurodevelopmental disorder characterized by significantly impaired intellectual and adaptive functioning. X-linked ID (XLID) disorders, caused by defects in genes on the X chromosome, affect...
9.
Wongkittichote P, Choi T, Kim O, Riley K, Koeberl D, Narayanan V, et al.
Clin Genet . 2022 Oct; 103(2):167-178. PMID: 36250278
ZC4H2 (MIM# 300897) is a nuclear factor involved in various cellular processes including proliferation and differentiation of neural stem cells, ventral spinal patterning and osteogenic and myogenic processes. Pathogenic variants...
10.
Mat Zian N, Swain P, Mohd Faudzi S, Zakaria N, Ibrahim W, Abu Bakar N, et al.
Pharmaceuticals (Basel) . 2022 Apr; 15(4). PMID: 35455463
Clitoria ternatea Linn. (CT), or butterfly pea, is an Ayurvedic plant traditionally used as a brain tonic. Recently, it was reported to be of use in treating central nervous system...