Tabitha A Harrison
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Explore the profile of Tabitha A Harrison including associated specialties, affiliations and a list of published articles.
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95
Citations
2881
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Recent Articles
11.
Thomas M, Su Y, Rosenthal E, Sakoda L, Schmit S, Timofeeva M, et al.
Nat Commun
. 2023 Oct;
14(1):6147.
PMID: 37783704
Polygenic risk scores (PRS) have great potential to guide precision colorectal cancer (CRC) prevention by identifying those at higher risk to undertake targeted screening. However, current PRS using European ancestry...
12.
Bouras E, Kim A, Lin Y, Morrison J, Du M, Albanes D, et al.
Am J Clin Nutr
. 2023 Aug;
118(5):881-891.
PMID: 37640106
Background: Epidemiological and experimental evidence suggests that higher folate intake is associated with decreased colorectal cancer (CRC) risk; however, the mechanisms underlying this relationship are not fully understood. Genetic variation...
13.
Park H, Edelmann D, Canzian F, Seibold P, Harrison T, Hua X, et al.
Int J Cancer
. 2023 Aug;
153(9):1623-1634.
PMID: 37539667
We conducted the first large genome-wide association study to identify novel genetic variants that predict better (or poorer) prognosis in colorectal cancer patients receiving standard first-line oxaliplatin-based chemotherapy vs chemotherapy...
14.
Dimou N, Kim A, Flanagan O, Murphy N, Diez-Obrero V, Shcherbina A, et al.
Br J Cancer
. 2023 Jun;
129(3):511-520.
PMID: 37365285
Background: Diabetes is an established risk factor for colorectal cancer. However, the mechanisms underlying this relationship still require investigation and it is not known if the association is modified by...
15.
Lai J, Wong C, Schmidt D, Kapuscinski M, Alpen K, MacInnis R, et al.
Cancer Epidemiol Biomarkers Prev
. 2023 Jun;
32(9):1153-1159.
PMID: 37364297
Background: DEPendency of association on the number of Top Hits (DEPTH) is an approach to identify candidate susceptibility regions by considering the risk signals from overlapping groups of sequential variants...
16.
Aglago E, Kim A, Lin Y, Qu C, Evangelou M, Ren Y, et al.
Cancer Res
. 2023 May;
83(15):2572-2583.
PMID: 37249599
Significance: This gene-environment interaction analysis revealed a genetic locus in FMN1/GREM1 that interacts with body mass index in colorectal cancer risk, suggesting potential implications for precision prevention strategies.
17.
Georgeson P, Steinfelder R, Harrison T, Pope B, Zaidi S, Qu C, et al.
medRxiv
. 2023 Apr;
PMID: 37090539
Background And Aims: The microbiome has long been suspected of a role in colorectal cancer (CRC) tumorigenesis. The mutational signature SBS88 mechanistically links CRC development with the strain of harboring...
18.
Thomas M, Su Y, Rosenthal E, Sakoda L, Schmit S, Timofeeva M, et al.
medRxiv
. 2023 Feb;
PMID: 36789420
Polygenic risk scores (PRS) have great potential to guide precision colorectal cancer (CRC) prevention by identifying those at higher risk to undertake targeted screening. However, current PRS using European ancestry...
19.
Ugai T, Haruki K, Harrison T, Cao Y, Qu C, Chan A, et al.
Am J Gastroenterol
. 2023 Jan;
118(4):712-726.
PMID: 36707929
Introduction: Early-onset colorectal cancer diagnosed before the age of 50 years has been increasing. Likely reflecting the pathogenic role of the intestinal microbiome, which gradually changes across the entire colorectal...
20.
Ugai T, Akimoto N, Haruki K, Harrison T, Cao Y, Qu C, et al.
J Gastroenterol
. 2023 Jan;
58(3):229-245.
PMID: 36648535
Background: The pathogenic effect of colorectal tumor molecular features may be influenced by several factors, including those related to microbiota, inflammation, metabolism, and epigenetics, which may change along colorectal segments....