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T Sreenath

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Articles 14
Citations 721
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Recent Articles
1.
Furusato B, Tan S, Young D, Dobi A, Sun C, Mohamed A, et al.
Prostate Cancer Prostatic Dis . 2010 Jun; 13(3):228-37. PMID: 20585344
Gene fusions prevalent in prostate cancer (CaP) lead to the elevated expression of the ERG proto-oncogene. ERG activation present in 50-70% of prostate tumors underscores one of the most common...
2.
Sun C, Dobi A, Mohamed A, Li H, Thangapazham R, Furusato B, et al.
Oncogene . 2008 Jun; 27(40):5348-53. PMID: 18542058
The high prevalence of TMPRSS2-ERG rearrangements ( approximately 60%) in prostate cancer (CaP) leads to androgenic induction of the ETS-related gene (ERG) expression. However, the biological functions of ERG overexpression...
3.
Hatakeyama J, Philp D, Hatakeyama Y, Haruyama N, Shum L, Aragon M, et al.
J Dent Res . 2006 Jan; 85(2):144-9. PMID: 16434732
We previously reported that amelogenin isoforms M180 and leucine-rich amelogenin peptide (LRAP) are expressed in the periodontal region, and that their absence is associated with increased cementum defects in amelogenin-knockout...
4.
Opsahl S, Septier D, Aubin I, Guenet J, Sreenath T, Kulkarni A, et al.
Arch Oral Biol . 2005 Feb; 50(2):279-86. PMID: 15721162
Our objective was to study the teeth of a mutant mice fro/fro that display severe forms of osteogenesis imperfecta. One day and 8 week-old fro/fro and +/fro heterozygote mice (wild...
5.
Shashidharan P, Sandu D, Potla U, Armata I, Walker R, McNaught K, et al.
Hum Mol Genet . 2004 Nov; 14(1):125-33. PMID: 15548549
Early-onset dystonia is an autosomal dominant movement disorder associated with deletion of a glutamic acid residue in torsinA. We generated four independent lines of transgenic mice by overexpressing human DeltaE-torsinA...
6.
Gibson C, Yuan Z, Hall B, Longenecker G, Chen E, Thyagarajan T, et al.
J Biol Chem . 2001 Jun; 276(34):31871-5. PMID: 11406633
Dental enamel is the hardest tissue in the body and cannot be replaced or repaired, because the enamel secreting cells are lost at tooth eruption. X-linked amelogenesis imperfecta (MIM 301200),...
7.
Hirasawa M, Cho A, Sreenath T, Sauer B, Julien J, Kulkarni A
Neurosci Res . 2001 May; 40(2):125-32. PMID: 11377750
Gene targeting to disrupt gene expression in a temporal and spatial manner in a specific tissue using Cre recombinase-mediated gene inactivation has been proven to be useful to study in...
8.
Tanaka T, Veeranna , Ohshima T, Rajan P, Amin N, Cho A, et al.
J Neurosci . 2001 Feb; 21(2):550-8. PMID: 11160434
Cyclin-dependent kinase 5 (Cdk5) null mice exhibit a unique phenotype characterized by perinatal mortality, disrupted cerebral cortical layering attributable to abnormal neuronal migration, lack of cerebellar foliation, and chromatolytic changes...
9.
Thyagarajan T, Sreenath T, Cho A, Wright J, Kulkarni A
J Biol Chem . 2000 Dec; 276(14):11016-20. PMID: 11116156
Transforming growth factor (TGF)-beta1 is expressed in developing tooth from the initiation stage through adulthood. Odontoblast-specific expression of TGF-beta1 in the tooth continues throughout life; however, the precise biological functions...
10.
Sreenath T, Orosz A, Fujita K, Bieberich C
Prostate . 1999 Oct; 41(3):203-7. PMID: 10517879
Background: Hox genes encode transcriptional regulatory proteins that are largely responsible for establishing the body plan of all metazoan organisms. A subset of Hox genes is expressed during the period...