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T Seroz

Explore the profile of T Seroz including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 8
Citations 288
Followers 0
Related Specialties
Biochemistry
Molecular Biology
Genetics
Top 10 Co-Authors
J M Egly
J H Hoeijmakers
W Vermeulen
R Roy
C Perez
G Weeda
J Auriol
P Miniou
V Moncollin
J R Hwang
Published In
J Biol Chem
Curr Opin Genet Dev
Am J Hum Genet
Nucleic Acids Res
Cell
Affiliations
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Recent Articles
1.
Cloning of a human homolog of the yeast nucleotide excision repair gene MMS19 and interaction with transcription repair factor TFIIH via the XPB and XPD helicases
Seroz T, Winkler G, Auriol J, Verhage R, Vermeulen W, Smit B, et al.
Nucleic Acids Res . 2000 Nov; 28(22):4506-13. PMID: 11071939
Nucleotide excision repair (NER) removes UV-induced photoproducts and numerous other DNA lesions in a highly conserved 'cut-and-paste' reaction that involves approximately 25 core components. In addition, several other proteins have...
2.
p44/SSL1, the regulatory subunit of the XPD/RAD3 helicase, plays a crucial role in the transcriptional activity of TFIIH
Seroz T, Perez C, Bergmann E, Bradsher J, Egly J
J Biol Chem . 2000 Aug; 275(43):33260-6. PMID: 10924514
In order to unravel the mechanism that regulates transcription of protein-coding genes, we investigated the function of the p44 subunit of TFIIH, a basal transcription factor that is also involved...
3.
Genomic organization and promoter characterization of the mouse and human genes encoding p62 subunit of the transcription/DNA repair factor TFIIH
Perez C, Auriol J, Seroz T, Egly J
Gene . 1998 Jun; 213(1-2):73-82. PMID: 9630526
TFIIH, a multisubunit complex was shown to be involved in several biological fundamental mechanisms of the cell: transcription, nucleotide excision repair and cell cycle regulation. p62 is one of the...
4.
Cloning and characterization of p52, the fifth subunit of the core of the transcription/DNA repair factor TFIIH
Marinoni J, Roy R, Vermeulen W, Miniou P, Lutz Y, Weeda G, et al.
EMBO J . 1997 Mar; 16(5):1093-102. PMID: 9118947
TFIIH is a multiprotein factor involved in transcription and DNA repair and is implicated in DNA repair/transcription deficiency disorders such as xeroderma pigmentosum, Cockayne syndrome and trichothiodystrophy. Eight out of...
5.
The gene encoding p44, a subunit of the transcription factor TFIIH, is involved in large-scale deletions associated with Werdnig-Hoffmann disease
Burglen L, Seroz T, Miniou P, Lefebvre S, Burlet P, Munnich A, et al.
Am J Hum Genet . 1997 Jan; 60(1):72-9. PMID: 8981949
Mutations of the survival motor neurone gene (SMN) are associated with spinal muscular atrophy (SMA), a frequent lethal autosomal recessive disorder. In spite of this, no phenotype-genotype correlation was observed,...
6.
A 3' --> 5' XPB helicase defect in repair/transcription factor TFIIH of xeroderma pigmentosum group B affects both DNA repair and transcription
Hwang J, Moncollin V, Vermeulen W, Seroz T, van Vuuren H, Hoeijmakers J, et al.
J Biol Chem . 1996 Jul; 271(27):15898-904. PMID: 8663148
XPB is a subunit of the basal transcription factor TFIIH, which is also involved in nucleotide excision repair (NER) and potentially in cell cycle regulation. A frameshift mutation in the...
7.
TFIIH: a link between transcription, DNA repair and cell cycle regulation
Seroz T, Hwang J, Moncollin V, Egly J
Curr Opin Genet Dev . 1995 Apr; 5(2):217-21. PMID: 7613092
TFIIH is a basal transcription factor for protein-coding genes. It contains ERCC2, ERCC3, MO15 and cyclin H, polypeptides implicated in nucleotide excision repair or cell cycle regulation. The dysfunction of...
8.
The MO15 cell cycle kinase is associated with the TFIIH transcription-DNA repair factor
Roy R, Adamczewski J, Seroz T, Vermeulen W, Tassan J, Schaeffer L, et al.
Cell . 1994 Dec; 79(6):1093-101. PMID: 8001135
A protein kinase activity that phosphorylates the C-terminal domain (CTD) of RNA polymerase II and is associated with the basal transcription-repair factor TFIIH (also called BTF2) resides with MO15, a...