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T Sage

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Articles 19
Citations 261
Followers 0
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Recent Articles
1.
Sasikumar P, AlOuda K, Kaiser W, Holbrook L, Kriek N, Unsworth A, et al.
J Thromb Haemost . 2018 Mar; 16(5):946-959. PMID: 29512284
Summary: Objective Heat shock protein 47 (HSP47) is an intracellular chaperone protein that is vital for collagen biosynthesis in collagen secreting cells. This protein has also been shown to be...
2.
Unsworth A, Kriek N, Bye A, Naran K, Sage T, Flora G, et al.
J Thromb Haemost . 2016 Nov; 15(2):356-369. PMID: 27896950
Summary: Background Agonists for the peroxisome proliferator-activated receptor (PPARγ) have been shown to have inhibitory effects on platelet activity following stimulation by GPVI and GPCR agonists. Objectives Profound effects on...
3.
Cancel A, Comte M, Truillet R, Boukezzi S, Rousseau P, Zendjidjian X, et al.
Acta Psychiatr Scand . 2015 Jun; 132(4):244-56. PMID: 26038817
Objective: Psychosocial trauma during childhood is associated with schizophrenia vulnerability. The pattern of grey matter decrease is similar to brain alterations seen in schizophrenia. Our objective was to explore the...
4.
Jones C, Tucker K, Sasikumar P, Sage T, Kaiser W, Moore C, et al.
J Thromb Haemost . 2014 Jun; 12(8):1342-52. PMID: 24888521
Background: Integrin-linked kinase (ILK) and its associated complex of proteins are involved in many cellular activation processes, including cell adhesion and integrin signaling. We have previously demonstrated that mice with...
5.
Sparagano O, Sage T, Fossi M, Lari L, Child P, Savva D, et al.
Biomarkers . 2013 Jul; 4(3):203-13. PMID: 23885863
As part of a programme to develop biomarker assays for polycyclic aromatic hydrocarbons (PAHs) in marine invertebrates, two species of crabs, Carcinus maenas and Carcinus aestuarii were exposed to benzo(a)pyrene...
6.
Sage T, Gagneret-Chague C, Benony H
Ann Dermatol Venereol . 2011 Jun; 138(6-7):545-8. PMID: 21700082
No abstract available.
7.
Moraes L, Barrett N, Jones C, Holbrook L, Spyridon M, Sage T, et al.
J Thromb Haemost . 2010 Aug; 8(11):2530-41. PMID: 20723025
Background: Platelet activation by collagen depends on signals transduced by the glycoprotein (GP)VI-Fc receptor (FcR)γ-chain collagen receptor complex, which involves recruitment of phosphatidylinositol 3-kinase (PI3K) to phosphorylated tyrosines in the...
8.
Moraes L, Spyridon M, Kaiser W, Jones C, Sage T, Atherton R, et al.
J Thromb Haemost . 2009 Dec; 8(3):577-87. PMID: 20040043
Background: Peroxisome proliferator-activated receptor-(gamma) (PPAR(gamma)) is expressed in human platelets although in the absence of genomic regulation in these cells, its functions are unclear. Objective: In the present study, we...
9.
Barrett N, Holbrook L, Jones S, Kaiser W, Moraes L, Rana R, et al.
Br J Pharmacol . 2008 Jul; 154(5):918-39. PMID: 18587441
Platelets have long been recognized to be of central importance in haemostasis, but their participation in pathological conditions such as thrombosis, atherosclerosis and inflammation is now also well established. The...
10.
Stevens J, Jordan P, Sage T, Gibbins J
J Thromb Haemost . 2004 Aug; 2(8):1443-52. PMID: 15304053
Background: Activation of the platelet integrin alpha 2 beta 1 is closely regulated due to the high thrombogenicity of its ligand. As a beta 1 interacting kinase, ILK represents a...