T S Blackwell
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Explore the profile of T S Blackwell including associated specialties, affiliations and a list of published articles.
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38
Citations
1403
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Recent Articles
1.
Polosukhin V, Polosukhin I, Hoskins A, Han W, Abdolrasulnia R, Blackwell T, et al.
Allergy
. 2014 Aug;
69(12):1666-72.
PMID: 25118837
Background: Glutathione S-transferase M1 (GSTM1) is a phase II enzyme and regulator of inflammatory signaling in airway epithelial cells. We have found upregulation of neutrophilic airway inflammation in atopic asthmatics...
2.
Zaynagetdinov R, Stathopoulos G, Sherrill T, Cheng D, McLoed A, Ausborn J, et al.
Oncogene
. 2011 Oct;
31(26):3164-76.
PMID: 22002309
The mechanisms by which chronic inflammatory lung diseases, particularly chronic obstructive pulmonary disease, confer enhanced risk for lung cancer are not well-defined. To investigate whether nuclear factor (NF)-κB, a key...
3.
Connelly L, Barham W, Onishko H, Sherrill T, Chodosh L, Blackwell T, et al.
Oncogene
. 2010 Nov;
30(12):1402-12.
PMID: 21076466
The transcription factor nuclear factor kappa B (NF-κB) is activated in human breast cancer tissues and cell lines. However, it is unclear whether NF-κB activation is a consequence of tumor...
4.
Boomershine C, Chamberlain A, Kendall P, Afshar-Sharif A, Huang H, Washington M, et al.
Gut
. 2009 Jul;
58(9):1267-74.
PMID: 19625278
Background And Aims: Autoimmune pancreatitis (AIP) is a poorly understood human disease affecting the exocrine pancreas. The goal of the present study was to elucidate the pathogenic mechanisms underlying pancreatic...
5.
Chen S, Cheng D, Williams B, Sherrill T, Han W, Chont M, et al.
Clin Exp Immunol
. 2008 Jul;
153(3):420-8.
PMID: 18647324
Pseudomonas aeruginosa pneumonia usually results from a deficit of the innate immune system. To investigate whether inflammatory signalling by airway epithelial cells provides a pivotal line of defence against P....
6.
Park G, Hu N, Wang X, Sadikot R, Yull F, Joo M, et al.
Clin Exp Immunol
. 2007 Aug;
150(2):245-54.
PMID: 17672868
Cyclooxygenase-2 (COX-2) gene expression in the lung is induced in pathological conditions such as asthma and pneumonia; however, the exact impact of COX-2 gene expression in the airway in regulating...
7.
Curran C, Blackwell T, Christman J
Expert Opin Ther Targets
. 2005 Jul;
5(2):197-204.
PMID: 15992176
The transcription factor NF-kappaB has been implicated in the pathogenesis of a variety of both acute and chronic inflammatory diseases. Many agents have shown promise and potential to abrogate NF-kappaB...
8.
Lawson W, Grant S, Ambrosini V, Womble K, Dawson E, Lane K, et al.
Thorax
. 2004 Nov;
59(11):977-80.
PMID: 15516475
Background: While idiopathic pulmonary fibrosis (IPF) is one of the most common forms of interstitial lung disease, the aetiology of IPF is poorly understood. Familial cases of pulmonary fibrosis suggest...
9.
Sadikot R, Christman J, Blackwell T
Curr Drug Targets
. 2004 Jul;
5(6):581-8.
PMID: 15270205
The inflammatory response of the lung and airways is one of the main targets for tile development of new therapies for variety of disorders including the acute respiratory distress syndrome,...
10.
Lee Y, Lane K, Zoia O, Thompson P, Light R, Blackwell T
Eur Respir J
. 2003 Sep;
22(2):197-202.
PMID: 12952247
Conventional pleurodesing agents often provoke acute pleural inflammation followed by fibrosis. The inflammation frequently causes pain and fever. Transforming growth factor (TGF)-beta is a pro-fibrotic but anti-inflammatory cytokine. Intrapleural TGF-beta2...