T S Anantha Samy
Overview
Explore the profile of T S Anantha Samy including associated specialties, affiliations and a list of published articles.
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9
Citations
89
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Recent Articles
1.
Zheng R, Pan G, Thobe B, Choudhry M, Matsutani T, Samy T, et al.
Mol Med
. 2006 Sep;
12(4-6):65-73.
PMID: 16953563
Hypoxia produces sex dimorphic immune responses in males and proestrus females. Because Kupffer cells are the major source of proinflammatory cytokines, studies were conducted to discern IL-6 production in mouse...
2.
Matsutani T, Samy T, Kang S, Bland K, Chaudry I
Cytokine
. 2005 May;
30(4):168-76.
PMID: 15863390
Studies have shown that following bacterial infection or endotoxin administration, immune functions are regulated differently in mice of different genetic background. Since the susceptibility to sepsis following trauma-hemorrhage is dependant...
3.
Matsutani T, Samy T, Rue 3rd L, Bland K, Chaudry I
Am J Physiol Cell Physiol
. 2004 Dec;
288(5):C1109-16.
PMID: 15601751
Prolactin (PRL) is involved in the regulation of immune functions under normal and pathological conditions. Trauma-hemorrhage (T-H) produces profound immunosuppression in male mice but not in proestrus female mice. Administration...
4.
Knoferl M, Angele M, Schwacha M, Samy T, Bland K, Chaudry I
Cell Immunol
. 2003 Jun;
222(1):27-34.
PMID: 12798305
Immune responses in proestrus females are not altered after trauma-hemorrhage, whereas they are markedly depressed in males. Elevated levels of female sex steroids appear to be responsible for maintaining immune...
5.
Chaudry I, Samy T, Schwacha M, Wang P, Rue 3rd L, Bland K
J Trauma
. 2003 May;
54(5 Suppl):S118-25.
PMID: 12768113
Modified resuscitation regimens and cytokine blockade/receptor antagonism after trauma have not been successful in decreasing the mortality rates from sepsis in trauma patients; therefore, an alternative approach using endocrine targets...
6.
Schneider C, Schwacha M, Samy T, Bland K, Chaudry I
J Appl Physiol (1985)
. 2003 Apr;
95(1):104-12.
PMID: 12665535
Androgens have been implicated as the causative factor for the postinjury immune dysfunction in males; however, it remains unknown whether androgens directly affect macrophages. To study this, male mice were...
7.
Samy T, Zheng R, Matsutani T, Rue 3rd L, Bland K, Chaudry I
Am J Physiol Cell Physiol
. 2003 Mar;
285(1):C139-49.
PMID: 12660147
Trauma-hemorrhage and resuscitation (TH) produces profound immunodepression and enhances susceptibility to sepsis in males but not in proestrus females, suggesting gender dimorphism in the immune responses. However, the mechanism responsible...
8.
Yokoyama Y, Schwacha M, Samy T, Bland K, Chaudry I
Immunol Res
. 2002 Oct;
26(1-3):63-76.
PMID: 12403346
Previous studies have shown marked immunosuppression in males after trauma and hemorrhage. By contrast, immunosuppression was not evident in proestrous female animals. Further support for these findings came from studies...
9.
Zheng R, Samy T, Schneider C, Rue 3rd L, Bland K, Chaudry I
Am J Physiol Cell Physiol
. 2002 May;
282(6):C1332-8.
PMID: 11997248
Trauma-hemorrhage produces profound immunosuppression in males but not in proestrus females. Prior castration or flutamide treatment of males following trauma-hemorrhage prevents immunosuppression, implicating 5alpha-dihydrotestosterone for the immunosuppressive effects. 5alpha-dihydrotestosterone, a...