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T R Van De Water

Explore the profile of T R Van De Water including associated specialties, affiliations and a list of published articles. Areas
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Articles 114
Citations 1453
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Recent Articles
1.
Jia H, Francois F, Bourien J, Eybalin M, Lloyd R, Van De Water T, et al.
Neuroscience . 2016 Jan; 316:261-78. PMID: 26718602
Cochlear fibrosis is a common finding following cochlear implantation. Evidence suggests that cochlear fibrosis could be triggered by inflammation and epithelial-to-mesenchymal cell transition (EMT). In this study, we investigate the...
2.
Bas E, Van De Water T, Gupta C, Dinh J, Vu L, Martinez-Soriano F, et al.
Br J Pharmacol . 2012 Feb; 166(6):1888-904. PMID: 22320124
BACKGROUND AND PURPOSE Exposure to an ototoxic level of an aminoglycoside can result in hearing loss. In this we study investigated the otoprotective efficacy of dexamethasone (DXM), melatonin (MLT) and...
3.
Eshraghi A, Dinh C, Bohorquez J, Angeli S, Abi-Hachem R, Van De Water T
Cochlear Implants Int . 2011 Jul; 12 Suppl 1:S51-3. PMID: 21756473
No abstract available.
4.
Dinh C, Bas E, Chan S, Dinh J, Vu L, Van De Water T
Neuroscience . 2011 May; 188:157-67. PMID: 21571041
The objective was to determine the role of nuclear factor kappa B (NFκB) in dexamethasone base (DXMb) protection of auditory hair cells from tumor necrosis factor-alpha (TNFα)-induced loss on gene...
5.
Malgrange B, Lefebvre P, Van De Water T, Bonnet C, Monville F, Rigo J, et al.
Toxicol In Vitro . 2010 Jul; 12(6):705-14. PMID: 20654460
The ototoxic damage that drugs such as neomycin, kanamycin, colistin, cisplatin, transplatin and carboplatin cause on outer and inner hair cells in postnatal day 3 rat cochlear explants was investigated....
6.
Dinh C, Haake S, Chen S, Hoang K, Nong E, Eshraghi A, et al.
Neuroscience . 2008 Oct; 157(2):405-13. PMID: 18838114
Objective: Determine the molecular mechanism(s) behind tumor necrosis factor-alpha (TNFalpha)-induced loss of auditory hair cells and the ability of dexamethasone base (DXMb) to protect against TNFalpha ototoxicity. Methods: Hair cell...
7.
Zine A, Van De Water T
Curr Drug Targets CNS Neurol Disord . 2004 Sep; 3(4):325-32. PMID: 15379608
The c-Jun N-terminal kinases (JNKs) are also called stress activated protein kinases (SAPKs) and are members of the family of mitogen activated protein kinases (MAPKs). While the functions of the...
8.
Van De Water T, Lallemend F, Eshraghi A, Ahsan S, He J, Guzman J, et al.
Otol Neurotol . 2004 Jul; 25(4):627-32. PMID: 15241246
This review covers the general roles of members of the cysteine protease family of caspases in the process of apoptosis (programmed cell death) looking at their participation in both the...
9.
Lallemend F, Lefebvre P, Hans G, Rigo J, Van De Water T, Moonen G, et al.
J Neurochem . 2003 Sep; 87(2):508-21. PMID: 14511128
In the current study, we have investigated the ability of substance P (SP) to protect 3-day-old (P3) rat spiral ganglion neurons (SGNs) from trophic factor deprivation (TFD)-induced cell death. The...
10.
Wang J, Van De Water T, Bonny C, de Ribaupierre F, Puel J, Zine A
J Neurosci . 2003 Sep; 23(24):8596-607. PMID: 13679429
Hearing loss can be caused by a variety of insults, including acoustic trauma and exposure to ototoxins, that principally effect the viability of sensory hair cells via the MAP kinase...