T R Tritton
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Explore the profile of T R Tritton including associated specialties, affiliations and a list of published articles.
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70
Citations
617
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Recent Articles
1.
Tritton T
Ann N Y Acad Sci
. 2001 Jun;
935:266-74.
PMID: 11411172
On the surface, higher education has served the nation well. An increasing percentage of adults have attended college. Information is widely and freely available to most citizens; the economy is...
2.
Maestre N, Tritton T, Laurent G, Jaffrezou J
Cancer Res
. 2001 Apr;
61(6):2558-61.
PMID: 11289131
Anthracyclines are, above all, DNA intercalators, which induce genetic damage leading to cell death. However, increasing evidence firmly suggests that the underlying mechanism for anthracycline cytotoxicity is the induction of...
3.
Zanella C, Timblin C, Cummins A, Jung M, Goldberg J, Raabe R, et al.
Am J Physiol
. 1999 Oct;
277(4):L684-93.
PMID: 10516208
We examined the mechanisms of interaction of crocidolite asbestos fibers with the epidermal growth factor (EGF) receptor (EGFR) and the role of the EGFR-extracellular signal-regulated kinase (ERK) signaling pathway in...
4.
Bhushan A, Hacker M, Tritton T
Braz J Med Biol Res
. 1999 Aug;
32(7):827-33.
PMID: 10454740
Resistance to anticancer drugs is a major cause of failure of many therapeutic protocols. A variety of mechanisms have been proposed to explain this phenomenon. The exact mechanism depends upon...
5.
Bhushan A, Kupperman J, Stone J, Kimberly P, Calman N, Hacker M, et al.
Immunol Cell Biol
. 1998 Sep;
76(4):350-6.
PMID: 9723776
It is demonstrated that methotrexate/cisplatin-sensitive L1210 cells express low levels of major histocompatibility complex (MHC) class II relative to the high levels expressed on methotrexate (MTX)/cisplatin-resistant L1210/DDP cells. L1210 cells...
6.
Penar P, Khoshyomn S, Bhushan A, Tritton T
In Vivo
. 1998 May;
12(1):75-84.
PMID: 9575429
Glioblastoma multiforme is a malignant primary brain tumor associated with short patient survival in part because of the ability of individual cells to migrate significant distances into brain tissue. Invasion...
7.
Xuan Y, Hacker M, Tritton T, Bhushan A
Oncol Rep
. 1998 Apr;
5(2):419-21.
PMID: 9468571
We have previously shown that methotrexate (MTX) transport is impaired in murine L1210 cells selected for cisplatin (DDP) resistance (L1210/DDP) and that the decreased MTX uptake may be due to...
8.
Penar P, Khoshyomn S, Bhushan A, Tritton T
Neurosurgery
. 1997 Jan;
40(1):141-51.
PMID: 8971836
Objective: Glioblastoma multiforme is a malignant primary brain tumor associated with short patient survival despite aggressive treatment, in part because of its propensity to aggressively infiltrate into brain tissue. Glioblastoma...
9.
Zanella C, Posada J, Tritton T, Mossman B
Cancer Res
. 1996 Dec;
56(23):5334-8.
PMID: 8968079
Asbestos fibers are human carcinogens with undefined mechanisms of action. In studies here, we examined signal transduction events induced by asbestos in target cells of mesothelioma and potential cell surface...
10.
Bhushan A, Slapak C, Levy S, Tritton T
Biochem Biophys Res Commun
. 1996 Sep;
226(3):819-21.
PMID: 8831695
Expression of murine P-glycoprotein (P-gp), encoded by mdrl or mdri3, confers a multidrug resistance phenotype. Higher expression of c-fos and c-jun has also been demonstrated in multidrug resistant human and...