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T R Torgerson

Explore the profile of T R Torgerson including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 6
Citations 402
Followers 0
Related Specialties
Allergy & Immunology
General Surgery
Biochemistry
Top 10 Co-Authors
J Hawiger
A D Colosia
H D Ochs
Y Z Lin
S Y Yao
W M Leisenring
R Storb
X Y Liu
J L Gallagher
L Zhang
Published In
J Clin Immunol
J Biol Chem
Bone Marrow Transplant
Proc Natl Acad Sci U S A
J Immunol
Affiliations
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Recent Articles
1.
Successful haploidentical donor hematopoietic stem cell transplant and restoration of STAT3 function in an adolescent with autosomal dominant hyper-IgE syndrome
Patel N, Gallagher J, Torgerson T, Gilman A
J Clin Immunol . 2015 May; 35(5):479-85. PMID: 25962528
Purpose: Autosomal dominant hyper-IgE syndrome (AD-HIES), caused by mutations in Signal Transducer and Activator of Transcription 3 (STAT3) is associated with defective STAT3 signaling and Th17 differentiation and recurrent bacterial...
2.
Primary immune deficiency disorders presenting as autoimmune diseases: IPEX and APECED
Moraes-Vasconcelos D, Costa-Carvalho B, Torgerson T, Ochs H
J Clin Immunol . 2008 Feb; 28 Suppl 1:S11-9. PMID: 18264745
Background: Several primary immune deficiency disorders are associated with autoimmunity and malignancy, suggesting a state of immune dysregulation. The concept of immune dysregulation as a direct cause of autoimmunity in...
3.
Intensive postgrafting immune suppression combined with nonmyeloablative conditioning for transplantation of HLA-identical hematopoietic cell grafts: results of a pilot study for treatment of primary immunodeficiency disorders
Burroughs L, Storb R, Leisenring W, Pulsipher M, Loken M, Torgerson T, et al.
Bone Marrow Transplant . 2007 Jul; 40(7):633-42. PMID: 17660844
This study was designed to determine the safety of a nonmyeloablative regimen in patients with primary immunodeficiency disorders (PID) who had infections, organ dysfunction or other risk factors that precluded...
4.
Regulation of NF-kappa B, AP-1, NFAT, and STAT1 nuclear import in T lymphocytes by noninvasive delivery of peptide carrying the nuclear localization sequence of NF-kappa B p50
Torgerson T, Colosia A, DONAHUE J, Lin Y, Hawiger J
J Immunol . 1998 Dec; 161(11):6084-92. PMID: 9834092
Activation of T lymphocytes by Ags or cytokines results in translocation of the transcription factors NF-kappa B, AP-1, NFAT, and STAT from the cytoplasm into the nucleus. The first step...
5.
Preparation of functionally active cell-permeable peptides by single-step ligation of two peptide modules
Zhang L, Torgerson T, Liu X, Timmons S, Colosia A, Hawiger J, et al.
Proc Natl Acad Sci U S A . 1998 Aug; 95(16):9184-9. PMID: 9689055
Noninvasive cellular import of synthetic peptides can be accomplished by incorporating a hydrophobic, membrane-permeable sequence (MPS). Herein, we describe a facile method that expedites synthesis of biologically active, cell-permeable peptides...
6.
Inhibition of nuclear translocation of transcription factor NF-kappa B by a synthetic peptide containing a cell membrane-permeable motif and nuclear localization sequence
Lin Y, Yao S, Veach R, Torgerson T, Hawiger J
J Biol Chem . 1995 Jun; 270(24):14255-8. PMID: 7782278
To control agonist-induced nuclear translocation of transcription factor kappa B (NF-kappa B) in intact cells, cell-permeable synthetic peptides were devised. Their import into intact cells was dependent on a hydrophobic...