T Prospero
Overview
Explore the profile of T Prospero including associated specialties, affiliations and a list of published articles.
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Articles
10
Citations
511
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Recent Articles
1.
Hartmann G, Prospero T, Brinkmann V, Ozcelik C, Winter G, Hepple J, et al.
Curr Biol
. 1998 Apr;
8(3):125-34.
PMID: 9443912
Background: Although a number of growth factors bind cell-surface heparan sulphate proteoglycans (HSPGs), the role of this interaction is unclear except for fibroblast growth factor which requires HSPG binding for...
2.
Doorbar J, Foo C, Coleman N, Medcalf L, Hartley O, Prospero T, et al.
Virology
. 1997 Dec;
238(1):40-52.
PMID: 9375007
HPV late gene expression is initiated as an infected basal cell migrates through the differentiating layers of the epidermis, resulting in the onset of vegetative viral DNA replication and the...
3.
Neri D, Prospero T, Petrul H, Winter G, Browne M, Vanderpant L
Biotechniques
. 1996 Apr;
20(4):708-13.
PMID: 8800693
Many applications in molecular biology require the rapid and high-sensitivity detection of biological macromolecules. Here we describe a luminescence analyzer (LUANA), featuring xenon lamp-based illumination and a cooled CCD camera...
4.
Neri D, Momo M, Prospero T, Winter G
J Mol Biol
. 1995 Feb;
246(3):367-73.
PMID: 7533215
We have developed a strategy for making antibody fragments with high binding affinities by harnessing the chelate effect. We create a bispecific antibody fragment (Chelating Recombinant Antibody or CRAb) that...
5.
Holliger P, Prospero T, Winter G
Proc Natl Acad Sci U S A
. 1993 Jul;
90(14):6444-8.
PMID: 8341653
Bivalent and bispecific antibodies and their fragments have immense potential for practical application. Here we describe the design of small antibody fragments with two antigen-binding sites. The fragments comprise a...
6.
Blattner J, Swinkels B, Dorsam H, Prospero T, Subramani S, Clayton C
J Cell Biol
. 1992 Dec;
119(5):1129-36.
PMID: 1447292
Trypanosomes compartmentalize most of their glycolytic enzymes in a peroxisome-like microbody, the glycosome. The specificity of glycosomal targeting was examined by expression of chloramphenicol acetyltransferase fusion proteins in trypanosomes and...
7.
Kabelitz D, Bender A, Prospero T, Wesselborg S, Janssen O, Pechhold K
J Exp Med
. 1991 Jun;
173(6):1331-8.
PMID: 1827825
We have previously reported that peripheral blood gamma/delta + T cells proliferate in high frequency (1 in 2-20) in response to heat-killed Mycobacterium tuberculosis (M.tb.). In the present study, the...
8.
Nash A, Jayasuriya A, Phelan J, Cobbold S, Waldmann H, Prospero T
J Gen Virol
. 1987 Mar;
68 ( Pt 3):825-33.
PMID: 2950204
Rat monoclonal antibodies were used to deplete selectively Lyt 2 (cytotoxic) and L3T4 (helper) T cell populations in vivo. These antibodies produced greater than 95% depletion of the respective T...
9.
Hale G, Hoang T, Prospero T, Watt S, Waldmann H
Mol Biol Med
. 1983 Oct;
1(3):305-19.
PMID: 6390085
We describe a family of six rat monoclonal antibodies which appear to recognize identical or closely related determinants present on virtually all mature human lymphocytes and monocytes, but absent from...
10.
Zamoyska R, Waldman H, Prospero T, LENNOX E
Mol Biol Med
. 1983 Jul;
1(1):137-50.
PMID: 6333573
Two distinct subpopulations of cytotoxic T lymphocytes (CTL) were identified on the basis of their expression of a marker recognized by a monoclonal antibody H9/25. Conventional bulk mixed lymphocyte reactions...