T P Loisel
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Explore the profile of T P Loisel including associated specialties, affiliations and a list of published articles.
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14
Citations
989
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Recent Articles
1.
Loisel T, Boujemaa R, Pantaloni D, Carlier M
Nature
. 1999 Oct;
401(6753):613-6.
PMID: 10524632
Actin polymerization is essential for cell locomotion and is thought to generate the force responsible for cellular protrusions. The Arp2/3 complex is required to stimulate actin assembly at the leading...
2.
Loisel T, Ansanay H, Adam L, Marullo S, Seifert R, Lagace M, et al.
J Biol Chem
. 1999 Oct;
274(43):31014-9.
PMID: 10521499
Palmitoylation is unique among lipid modifications in that it is reversible. In recent years, dynamic palmitoylation of G protein alpha subunits and of their cognate receptors has attracted considerable attention....
3.
Egile C, Loisel T, Laurent V, Li R, Pantaloni D, Sansonetti P, et al.
J Cell Biol
. 1999 Sep;
146(6):1319-32.
PMID: 10491394
To propel itself in infected cells, the pathogen Shigella flexneri subverts the Cdc42-controlled machinery responsible for actin assembly during filopodia formation. Using a combination of bacterial motility assays in platelet...
4.
Laurent V, Loisel T, Harbeck B, Wehman A, Grobe L, Jockusch B, et al.
J Cell Biol
. 1999 Mar;
144(6):1245-58.
PMID: 10087267
Intracellular propulsion of Listeria monocytogenes is the best understood form of motility dependent on actin polymerization. We have used in vitro motility assays of Listeria in platelet and brain extracts...
5.
Hebert T, Loisel T, Adam L, Ethier N, Onge S, Bouvier M
Biochem J
. 1998 Apr;
330 ( Pt 1):287-93.
PMID: 9461522
We have recently demonstrated that wild-type beta2-adrenergic receptors (beta2AR) form homodimers and that disruption of receptor dimerization inhibits signalling via Gs [Hebert, Moffett, Morello, Loisel, Bichet, Barret and Bouvier (1996)...
6.
Loisel T, Ansanay H, Gay B, BOULANGER P, Strosberg A, Marullo S, et al.
Nat Biotechnol
. 1997 Nov;
15(12):1300-4.
PMID: 9359116
Expression in baculovirus-infected insect cells allows sufficient production of G-protein coupled receptor for structural studies. An important drawback of this expression system comes from the presence of unprocessed and biologically...
7.
Loisel T, Adam L, Hebert T, Bouvier M
Biochemistry
. 1996 Dec;
35(49):15923-32.
PMID: 8961959
We have characterized the dynamic nature of beta 2-adrenergic receptor palmitoylation in Sf9 cells. Under basal conditions, the turnover of receptor-bound palmitate is rapid (half-life = 9.8 +/- 1.8 min)...
8.
Moffett S, Adam L, Bonin H, Loisel T, Bouvier M, Mouillac B
J Biol Chem
. 1996 Aug;
271(35):21490-7.
PMID: 8702933
We previously showed that substitution of a glycine residue for the palmitoylated cysteine 341 of the human beta2-adrenergic receptor (Gly341beta2AR), increases the basal level of the receptor phosphorylation and reduces...
9.
Hebert T, Moffett S, Morello J, Loisel T, Bichet D, Barret C, et al.
J Biol Chem
. 1996 Jul;
271(27):16384-92.
PMID: 8663163
One of the assumptions of the mobile receptor hypothesis as it relates to G protein-coupled receptors is that the stoichiometry of receptor, G protein, and effector is 1:1:1 (Bourne, H....
10.
Valiquette M, Parent S, Loisel T, Bouvier M
EMBO J
. 1995 Nov;
14(22):5542-9.
PMID: 8521811
The ability of insulin to promote phosphorylation of the human beta 2-adrenergic receptor (beta 2AR) was assessed in Chinese hamster fibroblasts transfected with beta 2AR cDNA. Phosphotyrosine residues were detected...