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T P Ciaraldi

Explore the profile of T P Ciaraldi including associated specialties, affiliations and a list of published articles. Areas
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Articles 61
Citations 1091
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Recent Articles
11.
Chalfant C, Ciaraldi T, Watson J, Nikoulina S, Henry R, Cooper D
Endocrinology . 2000 Aug; 141(8):2773-8. PMID: 10919262
Protein kinase C (PKCtheta) is a key enzyme in regulating a variety of cellular functions, including growth and differentiation. PKCtheta is the most abundant PKC isoform expressed in skeletal muscle;...
12.
Nikoulina S, Ciaraldi T, Mudaliar S, Mohideen P, Carter L, Henry R
Diabetes . 2000 Jun; 49(2):263-71. PMID: 10868943
Glycogen synthase (GS) activity is reduced in skeletal muscle of type 2 diabetes, despite normal protein expression, consistent with altered GS regulation. Glycogen synthase kinase-3 (GSK-3) is involved in regulation...
13.
Loviscach M, Rehman N, Carter L, Mudaliar S, Mohadeen P, Ciaraldi T, et al.
Diabetologia . 2000 Apr; 43(3):304-11. PMID: 10768091
Aims/hypothesis: To evaluate the tissue distribution and possible role of the peroxisome proliferator-activated receptors (PPARs) in insulin action in fat and muscle biopsy specimens from lean, obese and subjects with...
14.
Kim Y, Nikoulina S, Ciaraldi T, Henry R, Kahn B
J Clin Invest . 1999 Sep; 104(6):733-41. PMID: 10491408
To determine whether the serine/threonine kinase Akt (also known as protein kinase B) is activated in vivo by insulin administration in humans, and whether impaired activation of Akt could play...
15.
Ciaraldi T, Carter L, Nikoulina S, Mudaliar S, McClain D, Henry R
Endocrinology . 1999 Aug; 140(9):3971-80. PMID: 10465266
Chronic exposure (48 h) to glucosamine resulted in a dose-dependent reduction of basal and insulin-stimulated glucose uptake activities in human skeletal muscle cell cultures from nondiabetic and type 2 diabetic...
16.
Ciaraldi T, Carter L, Mudaliar S, Kern P, Henry R
Endocrinology . 1998 Dec; 139(12):4793-800. PMID: 9832415
The effects of tumor necrosis factor-alpha (TNF alpha) on glucose uptake and glycogen synthase (GS) activity were studied in human skeletal muscle cell cultures from nondiabetic and type 2 diabetic...
17.
Ciaraldi T, Morales A, Hickman M, Yen S, Olefsky J
Metabolism . 1998 Aug; 47(8):940-6. PMID: 9711989
Insulin resistance in polycystic ovary syndrome (PCOS) is characterized by a novel defect in insulin signal transduction expressed in isolated human adipocytes as impaired insulin sensitivity for glucose transport and...
18.
Park K, Ciaraldi T, Lindgren K, Mudaliar S, Nikoulina S, Tufari S, et al.
J Clin Endocrinol Metab . 1998 Aug; 83(8):2830-5. PMID: 9709955
Troglitazone, besides improving insulin action in insulin-resistant subjects, is also a specific ligand for the nuclear receptor peroxisome proliferator-activated receptor-gamma (PPARgamma). To determine whether troglitazone might enhance insulin action by...
19.
Park K, Ciaraldi T, Mudaliar S, Nikoulina S, Henry R
J Clin Endocrinol Metab . 1998 May; 83(5):1636-43. PMID: 9589670
To determine the effects of troglitazone on abnormal skeletal muscle glucose metabolism, muscle cultures from type II diabetic patients were grown for 4-6 weeks and then fused for 4 days...
20.
Ranganathan S, Ciaraldi T, Henry R, Mudaliar S, Kern P
Endocrinology . 1998 May; 139(5):2509-13. PMID: 9564865
The effect of leptin on glucose transport, lipogenesis, and lipoprotein lipase activity was studied in cultured rat adipocytes and 3T3-L1 adipocytes. Leptin had no effect on basal and insulin stimulated...