T P Abrahams
Overview
Explore the profile of T P Abrahams including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
146
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0
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Recent Articles
1.
Partosoedarso E, Abrahams T, Scullion R, Moerschbaecher J, Hornby P
J Physiol
. 2003 Jul;
550(Pt 1):149-58.
PMID: 12879865
Delta9-tetrahydrocannabinol (delta9-THC) is an effective anti-emetic; however, other potential gastrointestinal therapeutic effects of delta9-THC are less well-known. Here, we report a role of delta9-THC in a vago-vagal reflex that can...
2.
Abrahams T, Partosoedarso E, Hornby P
Neurogastroenterol Motil
. 2002 Jun;
14(3):295-304.
PMID: 12061915
An understanding of the neural control of lower oesophageal sphincter (LOS) relaxation is clinically relevant because transient LOS relaxations (TLOSRs) are a mechanism of acid reflux into the oesophagus. Preganglionic...
3.
McDermott C, Abrahams T, Partosoedarso E, Hyland N, Ekstrand J, Monroe M, et al.
Gastroenterology
. 2001 May;
120(7):1749-62.
PMID: 11375956
Background & Aims: Stimulation of gamma-aminobutyric acid B metabotropic receptors (GBRs) by baclofen reduces the incidence of transient lower esophageal sphincter (LES) relaxations. The GBR effect may be a result...
4.
Hyland N, Abrahams T, Fuchs K, Burmeister M, Hornby P
J Comp Neurol
. 2001 Jan;
430(2):222-34.
PMID: 11135258
The motor control of the lower esophageal sphincter (LES) is critical for normal swallowing and emesis, as well as for the prevention of gastroesophageal reflux. However, there are surprisingly few...
5.
Hornby P, Abrahams T
Am J Med
. 2000 Mar;
108 Suppl 4a:90S-98S.
PMID: 10718459
The lower esophageal sphincter is innervated by both parasympathetic (vagus) and sympathetic (primarily splanchnic) nerves; however, the vagal pathways are the ones that are essential for reflex relaxation of the...
6.
Krowicki Z, Sivarao D, Abrahams T, Hornby P
J Auton Nerv Syst
. 1999 Dec;
77(2-3):83-9.
PMID: 10580290
Vagal stimulation results in both gastric motor excitatory and non-adrenergic non-cholinergic (NANC) inhibitory responses. The NANC pathway involves preganglionic cholinergic neurons, which act through nicotinic receptors to ultimately evoke gastric...
7.
Sivarao D, Krowicki Z, Abrahams T, Hornby P
Eur J Pharmacol
. 1999 Apr;
368(2-3):173-82.
PMID: 10193653
Blockade of GABA(A) receptors in the dorsal vagal complex produces marked gastric motor excitation. This effect is abolished by a prior microinjection of a non-selective excitatory amino acid receptor antagonist....
8.
Abrahams T, Varner K
Physiol Behav
. 1998 Apr;
63(4):629-34.
PMID: 9523908
Cocaine increases the circulating levels of plasma catecholamines, presumably via the activation of the sympathoadrenal axis. However, a number of reports have shown that the predominant response to cocaine is...
9.
Sivarao D, Krowicki Z, Abrahams T, Hornby P
Am J Physiol
. 1997 Jun;
272(6 Pt 1):G1372-81.
PMID: 9227472
Thyrotropin-releasing hormone (TRH) from the nucleus raphe obscurus (nROb) innervates the dorsal vagal complex (DVC) and activates gastric motor function. Assessment of the importance of TRH has been hampered by...
10.
Abrahams T, Liu W, Varner K
J Pharmacol Exp Ther
. 1996 Nov;
279(2):967-74.
PMID: 8930206
The purpose of this study was to determine whether neurons in the rostral ventrolateral medulla play a role in the sympathoinhibitory response elicited by i.v. administration of cocaine and, if...