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K J Varner

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Articles 22
Citations 114
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1.
Shenouda S, Carvalho F, Varner K
Curr Pharm Biotechnol . 2010 Apr; 11(5):470-5. PMID: 20420571
The recreational use of 3, 4 methylenedioxymethamphetamine (ecstasy or MDMA) has increased dramatically over the past thirty years due to its ability to increase stamina and produce feelings of emotional...
2.
Varner K, Hein N, Ogden B, Arsenault J, Carter K, Soine W
Drug Alcohol Depend . 2001 Oct; 64(3):299-307. PMID: 11672944
Chloroephedrine is an intermediate and possible contaminant formed when methamphetamine is manufactured using ephedrine or pseudoephedrine as precursors. The purpose of this study was to determine whether this contaminant has...
3.
OCain P, Hletko S, Ogden B, Varner K
Physiol Behav . 2000 Sep; 70(1-2):141-8. PMID: 10978489
The recreational use of 3,4-methylenedioxymethamphetamine (MDMA) has increased as have the number of clinical reports linking MDMA use with cardiovascular toxicity. Nonetheless, the cardiovascular and sympathetic nerve responses elicited by...
4.
Rossoni L, Amaral S, Vassallo P, Franca A, Oliveira E, Varner K, et al.
Braz J Med Biol Res . 1999 Aug; 32(8):989-97. PMID: 10454761
The available data suggests that hypotension caused by Hg2+ administration may be produced by a reduction of cardiac contractility or by cholinergic mechanisms. The hemodynamic effects of an intravenous injection...
5.
Cabral A, Kapusta D, Kenigs V, Varner K
Am J Physiol . 1998 Dec; 275(6):R1867-74. PMID: 9843875
We have recently developed an experimental approach to study central opioid control of renal function in anesthetized rats. This model system uses the intravenous infusion of the alpha2-agonist xylazine to...
6.
Abrahams T, Varner K
Physiol Behav . 1998 Apr; 63(4):629-34. PMID: 9523908
Cocaine increases the circulating levels of plasma catecholamines, presumably via the activation of the sympathoadrenal axis. However, a number of reports have shown that the predominant response to cocaine is...
7.
Cabral A, Varner K, Kapusta D
J Pharmacol Exp Ther . 1997 Aug; 282(2):609-16. PMID: 9262322
This study examined the renal excretory responses produced by the intravenous (i.v.) infusion of the alpha-2 agonist, xylazine, in ketamine-anesthetized rats. In addition, the renal responses produced by the intracerebroventricular...
8.
Petersen J, Liu W, Kapusta D, Varner K
Hypertension . 1997 May; 29(5):1173-7. PMID: 9149683
Intravenous administration of the antihyperglycemic agent metformin decreases arterial pressure and sympathetic nerve activity (SNA). To test the hypothesis that metformin inhibits SNA by interrupting ganglionic neurotransmission, we compared the...
9.
Liu W, Varner K
J Cardiovasc Pharmacol . 1996 Nov; 28(5):712-22. PMID: 8945686
Although amphetamine has profound cardiovascular actions, the role of the sympathetic nervous system in these responses is largely unknown. The purpose of this study was to characterize the sympathetic nerve...
10.
Abrahams T, Liu W, Varner K
J Pharmacol Exp Ther . 1996 Nov; 279(2):967-74. PMID: 8930206
The purpose of this study was to determine whether neurons in the rostral ventrolateral medulla play a role in the sympathoinhibitory response elicited by i.v. administration of cocaine and, if...