T Orton
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Explore the profile of T Orton including associated specialties, affiliations and a list of published articles.
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5
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914
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Recent Articles
1.
Gould S, Sidaway J, Sansom N, Betton G, Orton T
Toxicol Lett
. 2001 Jul;
122(2):131-40.
PMID: 11439219
The tumour suppressor protein, p53, is involved in the regulation of apoptosis and growth arrest following DNA damage. Mutations of the p53 gene are found in 50-55% of all human...
2.
OBrien J, Wilson I, Orton T, Pognan F
Eur J Biochem
. 2000 Aug;
267(17):5421-6.
PMID: 10951200
We show here the identity of Alamar Blue as resazurin. The 'resazurin reduction test' has been used for about 50 years to monitor bacterial and yeast contamination of milk, and...
3.
Garcia-Allan C, Loughlin J, Orton T, Lord P
Arch Toxicol
. 1997 Jan;
71(7):409-15.
PMID: 9209685
The effects of phenobarbitone and methylclofenapate were studied on the expression of growth factor and growth factor receptors in livers of male Wistar rats. The major findings were: (1) a...
4.
Barrass N, Stewart M, Warburton S, AITCHISON J, Jackson D, Wadsworth P, et al.
Environ Health Perspect
. 1993 Dec;
101 Suppl 5:219-23.
PMID: 8013410
Chlordane is a polychlorinated hydrocarbon that causes liver enlargement and induces mixed-function oxidases similar to those induced by phenobarbitone in the mouse. We have assessed the hepatocarcinogenicity (after 2 years)...
5.
Greaves P, Goonetilleke R, Nunn G, Topham J, Orton T
Cancer Res
. 1993 Sep;
53(17):3919-24.
PMID: 8358718
Tamoxifen, a nonsteroidal antiestrogen used widely in the treatment of breast cancer, was tested in a conventional 2-year carcinogenicity bioassay in rats, a species in which tamoxifen acts variably as...