G Betton
Overview
Explore the profile of G Betton including associated specialties, affiliations and a list of published articles.
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6
Citations
464
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Recent Articles
1.
Brott D, Gould S, Jones H, Schofield J, Prior H, Valentin J, et al.
Toxicol Appl Pharmacol
. 2005 Jun;
207(2 Suppl):441-5.
PMID: 15982681
In pre-clinical safety studies, drug-induced vascular injury is an issue of concern because there are no obvious diagnostic markers for pre-clinical or clinical monitoring and there is an intellectual gap...
2.
Gould S, Sidaway J, Sansom N, Betton G, Orton T
Toxicol Lett
. 2001 Jul;
122(2):131-40.
PMID: 11439219
The tumour suppressor protein, p53, is involved in the regulation of apoptosis and growth arrest following DNA damage. Mutations of the p53 gene are found in 50-55% of all human...
3.
Broadhead C, Betton G, Combes R, Damment S, Everett D, Garner C, et al.
Hum Exp Toxicol
. 2000 Dec;
19(8):440-7.
PMID: 11125714
A workshop was held to critically discuss the need for a nonrodent species and the role of the dog in regulatory toxicity testing of pharmaceuticals; to discuss opportunities to reduce...
4.
Olson H, Betton G, Robinson D, Thomas K, MONRO A, Kolaja G, et al.
Regul Toxicol Pharmacol
. 2000 Oct;
32(1):56-67.
PMID: 11029269
This report summarizes the results of a multinational pharmaceutical company survey and the outcome of an International Life Sciences Institute (ILSI) Workshop (April 1999), which served to better understand concordance...
5.
Olson H, Betton G, Stritar J, Robinson D
Toxicol Lett
. 1999 Feb;
102-103:535-8.
PMID: 10022308
This project was undertaken by the International Life Sciences Institute's Health and Environmental Sciences Institute (ILSI-HESI) to develop an improved understanding of the extent to which various types of human...
6.
Betton G, Cockburn A, HARPUR E, Hopkins J, Illing P, Lumley C, et al.
Hum Exp Toxicol
. 1994 Apr;
13(4):221-32.
PMID: 8204306
This review indicates that for the detection of non-neoplastic toxic effects: 1. Four decades of accumulated literature provide no lead as to the optimum duration of repeat dose toxicity testing...