T Misteli
Overview
Explore the profile of T Misteli including associated specialties, affiliations and a list of published articles.
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42
Citations
3086
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Recent Articles
1.
Babahosseini H, Padmanabhan S, Misteli T, DeVoe D
Annu Int Conf IEEE Eng Med Biol Soc
. 2020 Jan;
2019:1054-1057.
PMID: 31946075
Formation, selective retrieval and capturing of individual droplets are key operational capabilities needed for a broad range of droplet microfluidic applications. The membrane displacement trap (MDT) element gives a robust...
2.
Padmanabhan S, Misteli T, DeVoe D
Lab Chip
. 2017 Oct;
17(21):3717-3724.
PMID: 28990023
An innovative platform enabling complex discretization and manipulation of aqueous droplets is described. The system uses simple membrane displacement trap elements to perform multiple functions including droplet discretization, release, metering,...
3.
Scaffidi P, Misteli T
Cold Spring Harb Symp Quant Biol
. 2010 Nov;
75:251-8.
PMID: 21047903
Cancer is a disease of the genome. Whereas efforts to understand the molecular basis of cancer have in the past largely focused on the role of mutations, recent evidence points...
4.
McCullough D, Gudla P, Harris B, Collins J, Meaburn K, Nakaya M, et al.
IEEE Trans Med Imaging
. 2008 May;
27(5):723-34.
PMID: 18450544
Communications between cells in large part drive tissue development and function, as well as disease-related processes such as tumorigenesis. Understanding the mechanistic bases of these processes necessitates quantifying specific molecules...
5.
Gudla P, Nandy K, Collins J, Meaburn K, Misteli T, Lockett S
Cytometry A
. 2008 Mar;
73(5):451-66.
PMID: 18338778
Automatic segmentation of cell nuclei is critical in several high-throughput cytometry applications whereas manual segmentation is laborious and irreproducible. One such emerging application is measuring the spatial organization (radial and...
6.
Kim S, McQueen P, Lichtman M, Shevach E, Parada L, Misteli T
Cytogenet Genome Res
. 2004 Jul;
105(2-4):292-301.
PMID: 15237218
The spatial organization of genomes within the mammalian cell nucleus is non-random. The functional relevance of spatial genome organization might be in influencing gene expression programs as cells undergo changes...
7.
Mahieux R, Pise-Masison C, Gessain A, Brady J, Olivier R, Perret E, et al.
Blood
. 2001 Dec;
98(13):3762-9.
PMID: 11739184
Treatment of patients with adult T-cell leukemia-lymphoma (ATLL) using conventional chemotherapy has limited benefit because human T-cell leukemia virus type 1 (HTLV-1) cells are resistant to most apoptosis-inducing agents. The...
8.
Phair R, Misteli T
Nat Rev Mol Cell Biol
. 2001 Dec;
2(12):898-907.
PMID: 11733769
The ability to visualize protein dynamics and biological processes by in vivo microscopy is revolutionizing many areas of biology. These methods generate large, kinetically complex data sets, which often cannot...
9.
Misteli T
J Cell Biol
. 2001 Oct;
155(2):181-5.
PMID: 11604416
In vivo microscopy has recently revealed the dynamic nature of many cellular organelles. The dynamic properties of several cellular structures are consistent with a role for self-organization in their formation,...
10.
Kalbfuss B, Mabon S, Misteli T
J Biol Chem
. 2001 Sep;
276(46):42986-93.
PMID: 11560926
Mutations in the human tau gene cause frontotemporal dementia and Parkinsonism associated with chromosome 17 (FTDP-17). One of the major disease mechanisms in FTDP-17 is the increased inclusion of tau...