T Lorenzini
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Explore the profile of T Lorenzini including associated specialties, affiliations and a list of published articles.
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8
Citations
120
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Recent Articles
1.
Cavallari E, de Lellis L, Stefanelli G, Lorenzini T
G Ital Med Lav Ergon
. 2008 Aug;
30(1):22-32.
PMID: 18700673
The D.Lgs 626/94, regarding the improvement of workers safety in the workplace, introduces the necessity of the biological hazards assessment. In case of not sanitary chemical and biological laboratories, workers...
2.
Elliott S, Lorenzini T, Chang D, Barzilay J, Delorme E
Blood
. 1997 Jan;
89(2):493-502.
PMID: 9002951
Recombinant human erythropoietin (rHuEPO) variants have been constructed to identify amino acid residues important for biological activity. Immunoassays were used to determine the effect of each mutation on rHuEPO folding....
3.
Schneider H, Chaovapong W, Matthews D, Karkaria C, Cass R, Zhan H, et al.
Blood
. 1997 Jan;
89(2):473-82.
PMID: 9002949
Erythropoietin (EPO) stimulates proliferation and differentiation of erythroid progenitor cells. Several lines of evidence indicate that the most likely mechanism of EPO receptor (EPO-R) activation by EPO is homodimerization of...
4.
Elliott S, Lorenzini T, Yanagihara D, Chang D, Elliott G
J Biol Chem
. 1996 Oct;
271(40):24691-7.
PMID: 8798737
Oligomerization of cytokine receptors including the erythropoietin (EPO) receptor has been advanced as a model for activation. If homodimerization of the EPO receptor activates it, then bivalent antibodies raised to...
5.
Elliott S, Chang D, Delorme E, Dunn C, Egrie J, Giffin J, et al.
Blood
. 1996 Apr;
87(7):2714-22.
PMID: 8639887
We have isolated and characterized three anti-recombinant human erythropoietin (rHuEPO) monoclonal antibodies (MoAbs) that recognize nonoverlapping epitopes on rHuEPO. Anti-EPO MoAb D11 neutralizes rHuEPO activity whereas MoAbs F12 and 9G8A...
6.
Elliott S, Lorenzini T, Chang D, Barzilay J, Delorme E, Giffin J, et al.
Blood
. 1996 Apr;
87(7):2702-13.
PMID: 8639886
We have isolated and mapped the rHuEPO epitopes for three noncompeting anti-EPO monoclonal antibodies (MoAbs). The MoAb 9G8A recognizes a linear epitope that includes amino acids 13, 16, and 17....
7.
Elliott S, Bartley T, Delorme E, Derby P, Hunt R, Lorenzini T, et al.
Biochemistry
. 1994 Sep;
33(37):11237-45.
PMID: 7727375
To define the structural requirements for addition of O-linked glycosylation in vivo, recombinant erythropoietin (rEPO) variants were constructed. Thirty-three independent Ser or Thr substitutions were constructed and examined to see...
8.
Delorme E, Lorenzini T, Giffin J, Martin F, Jacobsen F, Boone T, et al.
Biochemistry
. 1992 Oct;
31(41):9871-6.
PMID: 1390770
The erythropoietin (EPO) molecule contains four carbohydrate chains. Three contain N-linkages to asparagines at positions 24, 38, and 83, and one contains an O-linkage to a serine at position 126....