T L Rothstein
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Explore the profile of T L Rothstein including associated specialties, affiliations and a list of published articles.
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Articles
121
Citations
1932
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Recent Articles
1.
Cui X, Zhang L, Magli A, Catera R, Yan X, Griffin D, et al.
Leukemia
. 2015 Jul;
30(1):74-85.
PMID: 26220042
The degree of chronic lymphocytic leukemia (CLL) B-cell antigen receptor (BCR) binding to myosin-exposed apoptotic cells (MEACs) correlates with worse patient outcomes, suggesting a link to disease activity. Therefore, we...
2.
Kaku H, Rothstein T
Genes Immun
. 2009 Aug;
11(1):55-66.
PMID: 19710692
Programmed death-1 ligand 2 (PD-L2) expression extends beyond macrophages/dendritic cells to B-1 B cells, a distinct B-cell lineage that is responsible for natural immunoglobulin and which is repertoire skewed toward...
3.
Rothstein T, Guo B
J Intern Med
. 2009 Jun;
265(6):632-43.
PMID: 19493057
Receptor crosstalk: reprogramming B cell receptor signalling to an alternate pathway results in expression and secretion of the autoimmunity-associated cytokine, osteopontin (Review). J Intern Med 2009; 265: 632-643.Intracellular signalling emanating...
4.
Mizuno T, Zhong X, Rothstein T
Apoptosis
. 2003 Sep;
8(5):451-60.
PMID: 12975576
Engagement of the cell surface receptor Fas/APO-1 (CD95) initiates a sequence of intracellular events that leads to apoptotic cell death, and this outcome occurs in B cells as it does...
5.
Fischer G, Solt L, Hastings W, Yang K, Gerstein R, Nikolajczyk B, et al.
Cell Immunol
. 2001 Dec;
213(1):62-71.
PMID: 11747357
B-1 cells constitute a distinct B cell subset with characteristic phenotypic and functional features. B-1 cells are highly represented among peritoneal lymphocytes; substantial numbers of B-1 cells are also located...
6.
Owyang A, Tumang J, Schram B, Hsia C, Behrens T, Rothstein T, et al.
J Immunol
. 2001 Oct;
167(9):4948-56.
PMID: 11673501
The NF-kappaB/Rel transcription factor family has been shown to protect many cell types from apoptotic signals. However, it is not known whether NF-kappaB is required for all survival pathways and...
7.
Zhong X, Schneider T, Cabral D, Donohoe T, Rothstein T
Mol Immunol
. 2001 Aug;
38(1):65-72.
PMID: 11483211
The gene encoding Fas apoptosis inhibitory molecule (FAIM) was cloned by differential display using RNA obtained from Fas-resistant and Fas-sensitive primary murine B lymphocytes. FAIM is highly evolutionarily conserved and...
8.
Tanguay D, Colarusso T, Doughty C, Rothstein T, Chiles T
J Immunol
. 2001 Mar;
166(7):4273-7.
PMID: 11254678
B-1 lymphocytes represent a distinct B cell subset with unusual mitogenic responses. PMA alone promotes proliferation in B-1 cells, but not in splenic B-2 cells. Although cyclin D2-cyclin-dependent kinase 4...
9.
Rothstein T
Cell Res
. 2001 Feb;
10(4):245-66.
PMID: 11191348
Apoptosis produced in B cells through Fas (APO-1, CD95) triggering is regulated by signals derived from other surface receptors: CD40 engagement produces upregulation of Fas expression and marked susceptibility to...
10.
Fan H, Rothstein T
Eur J Immunol
. 2001 Feb;
31(2):665-71.
PMID: 11180132
Stimulation of B cells by surface immunoglobulin (sIg) triggering, or through the mitogenic combination of phorbol ester and calcium ionophore, is accompanied by activation of STAT transcription factors. The mechanism...