T L BENJAMIN
Overview
Explore the profile of T L BENJAMIN including associated specialties, affiliations and a list of published articles.
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83
Citations
2499
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Recent Articles
1.
Li D, Dower K, Ma Y, Tian Y, BENJAMIN T
Proc Natl Acad Sci U S A
. 2001 Dec;
98(25):14619-24.
PMID: 11734654
Cancer cells may undergo loss or alterations in functions that certain viruses normally target to promote virus replication. Virus mutants that have lost the targeting function(s) should be able to...
2.
BENJAMIN T
Virology
. 2001 Nov;
289(2):167-73.
PMID: 11689038
The accidental discovery of the mouse polyoma virus nearly 50 years ago opened up an experimental system unique in opportunities for investigating virus-host interactions leading to the development of tumors....
3.
Cho S, Tian Y, BENJAMIN T
J Biol Chem
. 2001 Jul;
276(36):33533-9.
PMID: 11438528
Small DNA tumor viruses such as simian virus 40 (SV40) and polyomavirus (Py) take advantage of host cell proteins to transcribe and replicate their DNA. Interactions between the viral T...
4.
Gilbert J, BENJAMIN T
J Virol
. 2000 Aug;
74(18):8582-8.
PMID: 10954560
The mechanism by which murine polyomavirus penetrates cells and arrives at the nucleus, the site of viral replication, is not well understood. Simian virus 40 and JC virus, two closely...
5.
Dey D, Bronson R, Dahl J, Carroll J, BENJAMIN T
Cell Growth Differ
. 2000 Jun;
11(5):231-7.
PMID: 10845423
Molecular evidence linking polyoma virus to p53 inactivation is thus far lacking, setting this highly oncogenic virus apart from other DNA tumor viruses. As a biological test for interaction, we...
6.
Velupillai P, Yoshizawa I, Dey D, Nahill S, Carroll J, Bronson R, et al.
J Virol
. 1999 Nov;
73(12):10079-85.
PMID: 10559322
Polyomavirus induces a broad array of tumors when introduced into newborn mice of certain standard inbred strains, notably those bearing the H-2(k) haplotype. Susceptibility in these mice is conferred by...
7.
Bauer P, Cui C, Liu W, Stehle T, Harrison S, DeCaprio J, et al.
J Virol
. 1999 Jun;
73(7):5826-32.
PMID: 10364334
Variations in the polyomavirus major capsid protein VP1 underlie important biological differences between highly pathogenic large-plaque and relatively nonpathogenic small-plaque strains. These polymorphisms constitute major determinants of virus spread in...
8.
Carroll J, Fung J, Bronson R, Razvi E, BENJAMIN T
J Virol
. 1999 Jan;
73(2):1213-8.
PMID: 9882323
Newborn mice of several inbred strains develop few or no tumors following inoculation with highly tumorigenic strains of polyomavirus. Here we show that such resistant strains can be divided into...
9.
Dahl J, Jurczak A, Cheng L, Baker D, BENJAMIN T
J Virol
. 1998 Apr;
72(4):3221-6.
PMID: 9525648
A polyomavirus mutant (315YF) blocked in binding phosphatidylinositol 3-kinase (PI 3-kinase) has previously been shown to be partially deficient in transformation and to induce fewer tumors and with a significant...
10.
Cullere X, Rose P, Thathamangalam U, Chatterjee A, Mullane K, Pallas D, et al.
J Virol
. 1998 Jan;
72(1):558-63.
PMID: 9420259
Polyomavirus middle T antigen (MT) is phosphorylated on serine residues. Partial proteolytic mapping and Edman degradation identified serine 257 as a major site of phosphorylation. This was confirmed by site-directed...