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T Komiyama

Explore the profile of T Komiyama including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 139
Citations 1044
Followers 0
Related Specialties
Biochemistry
Neurology
Science
Top 10 Co-Authors
H Shigematsu
M Harano
M Iyo
Y Sekine
I Sora
T Inada
N Ozaki
M Yamada
H Ujike
N Iwata
Published In
J Biochem
Ann N Y Acad Sci
Biochim Biophys Acta
Brain Res
Eur J Vasc Endovasc Surg
Affiliations
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Recent Articles
1.
Association of Lower-Extremity Muscle Performance and Physical Activity Level and Intensity in Middle-Aged and Older Adults: A Doubly Labeled Water and Accelerometer Study
Takae R, Hatamoto Y, Yasukata J, Kose Y, Komiyama T, Ikenaga M, et al.
J Nutr Health Aging . 2020 Nov; 24(9):1023-1030. PMID: 33155632
Objectives: The purpose of this study was to examine if there is a relationship between lower-extremity muscle performance (LEMP) and physical activity, especially the physical activity level (PAL) value, in...
2.
Practicalities of dose management for Japanese astronauts staying at the International Space Station
Komiyama T
Ann ICRP . 2020 Sep; 49(1_suppl):194-199. PMID: 32969256
Japanese astronauts started staying at the International Space Station (ISS) in 2009, with each stay lasting for approximately 6 months. In total, seven Japanese astronauts have stayed at the ISS...
3.
Maximum Occlusal Force and Incident Functional Disability in Older Adults: The Tsurugaya Project
Ohi T, Komiyama T, Miyoshi Y, Murakami T, Tsuboi A, Tomata Y, et al.
JDR Clin Trans Res . 2019 Apr; 3(2):195-202. PMID: 30931768
The purpose of the current study was to investigate the association between maximum occlusal force, which is an objective predictor of masticatory performance, and incident functional disability in an elderly...
4.
Teriparatide improves volumetric bone mineral density and fine bone structure in the UIV+1 vertebra, and reduces bone failure type PJK after surgery for adult spinal deformity
Yagi M, Ohne H, Konomi T, Fujiyoshi K, Kaneko S, Komiyama T, et al.
Osteoporos Int . 2016 Jun; 27(12):3495-3502. PMID: 27341809
Introduction: Proximal junctional kyphosis (PJK) is a complication after corrective surgery for spinal deformity. This study sought to determine whether teriparatide (TP) is an effective prophylactic against PJK type 2...
5.
Multidrug resistance protein 4 (MRP4) polymorphisms impact the 6-mercaptopurine dose tolerance during maintenance therapy in Japanese childhood acute lymphoblastic leukemia
Tanaka Y, Manabe A, Fukushima H, Suzuki R, Nakadate H, Kondoh K, et al.
Pharmacogenomics J . 2014 Nov; 15(4):380-4. PMID: 25403995
Multidrug resistance protein 4 (MRP4) is involved in the efflux of nucleoside derivatives and has a role in the determination of drug sensitivity. We investigated the relationship between MRP4 genetic...
6.
Association study of the calcineurin A gamma subunit gene (PPP3CC) and methamphetamine-use disorder in a Japanese population
Kinoshita Y, Ikeda M, Ujike H, Kitajima T, Yamanouchi Y, Aleksic B, et al.
Ann N Y Acad Sci . 2008 Nov; 1139:57-62. PMID: 18991849
Several lines of evidence from animal and genetic analyses showed that the calcineurin A gamma subunit gene (PPP3CC) plays an important role in the pathogenesis of schizophrenia. Moreover, a recent...
7.
Association study between casein kinase 1 epsilon gene and methamphetamine dependence
Kotaka T, Ujike H, Morita Y, Kishimoto M, Okahisa Y, Inada T, et al.
Ann N Y Acad Sci . 2008 Nov; 1139:43-8. PMID: 18991847
Casein kinase 1 epsilon (CKIepsilon) is a component of the DARPP-32 in second-messenger pathway. CKIepsilon phosphorylates and activates DARPP-32, a key molecule in various complex signaling pathways, including dopamine and...
8.
Trichostatin A, a histone deacetylase inhibitor, suppresses synovial inflammation and subsequent cartilage destruction in a collagen antibody-induced arthritis mouse model
Nasu Y, Nishida K, Miyazawa S, Komiyama T, Kadota Y, Abe N, et al.
Osteoarthritis Cartilage . 2008 Jan; 16(6):723-32. PMID: 18226559
Objective: To investigate the effect of the histone deacetylase (HDAC) inhibitor, trichostatin A (TSA), on joint inflammation and cartilage degeneration in a collagen antibody-induced arthritis (CAIA) mouse model. Methods: CAIA...
9.
Inhibition of histone deacetylase down-regulates the expression of hypoxia-induced vascular endothelial growth factor by rheumatoid synovial fibroblasts
Manabe H, Nasu Y, Komiyama T, Furumatsu T, Kitamura A, Miyazawa S, et al.
Inflamm Res . 2008 Jan; 57(1):4-10. PMID: 18209959
Objective: To investigate the effect of FK228 on the in vitro expression of hypoxia-inducible factor-1 alpha (HIF-1alpha) and vascular endothelial growth factor (VEGF) by rheumatoid arthritis synovial fibroblasts (RASFs), and...
10.
Intra-articular injection of interleukin-4 decreases nitric oxide production by chondrocytes and ameliorates subsequent destruction of cartilage in instability-induced osteoarthritis in rat knee joints
Yorimitsu M, Nishida K, Shimizu A, Doi H, Miyazawa S, Komiyama T, et al.
Osteoarthritis Cartilage . 2008 Jan; 16(7):764-71. PMID: 18182309
Objective: To investigate the in vitro and in vivo effects of interleukin (IL)-4 on mechanical stress-induced nitric oxide (NO) expression by chondrocytes, and destruction of cartilage and NO production in...