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T J Keen

Explore the profile of T J Keen including associated specialties, affiliations and a list of published articles. Areas
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Articles 29
Citations 486
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Recent Articles
1.
Huseby S, Gausdal G, Keen T, Kjaerland E, Krakstad C, Myhren L, et al.
Cell Death Dis . 2011 Dec; 2:e237. PMID: 22158476
The IPC-81 cell line is derived from the transplantable BNML model of acute myelogenic leukemia (AML), known to be a reliable predictor of the clinical efficiency of antileukemic agents, like...
2.
Kjarland E, Keen T, Kleppe R
Curr Pharm Biotechnol . 2006 Jun; 7(3):217-23. PMID: 16789906
The 14-3-3 family of proteins was originally identified in 1967 as simply an abundant brain protein. However it took almost 25 years before the ubiquitous role of 14-3-3 in cell...
3.
Pal B, Mohamed M, Keen T, Williams G, Bradbury J, Sheridan E, et al.
J Med Genet . 2004 Oct; 41(10):772-7. PMID: 15466012
No abstract available.
4.
McKie A, McHale J, Keen T, Tarttelin E, Goliath R, Greenberg J, et al.
Hum Mol Genet . 2001 Jul; 10(15):1555-62. PMID: 11468273
Retinitis pigmentosa (RP) is a genetically heterogeneous disorder characterized by progressive degeneration of the peripheral retina leading to night blindness and loss of visual fields. With an incidence of approximately...
5.
Downey L, Keen T, Roberts E, Mansfield D, Bamashmus M, Inglehearn C
Am J Hum Genet . 2001 Feb; 68(3):778-81. PMID: 11179025
We report a new locus for familial exudative vitreoretinopathy (FEVR), on chromosome 11p12-13 in a large autosomal dominant pedigree. Statistically significant linkage was achieved across a 14-cM interval flanked by...
6.
Inglehearn C, McHale J, Keen T, Skirton H, Lunt P
J Med Genet . 1999 Aug; 36(8):646-8. PMID: 10465120
No abstract available.
7.
Inglehearn C, Tarttelin E, Keen T, Bhattacharya S, Moore A, Taylor R, et al.
J Med Genet . 1998 Sep; 35(9):788-9. PMID: 9733043
No abstract available.
8.
Peacock R, Keen T, Inglehearn C
Genomics . 1998 Jan; 46(3):443-9. PMID: 9441748
We report on the analysis of a human gene homologous to the rat ventral prostate.1 protein (RVP.1), which is transcriptionally induced in the regressing rat prostate after castration. EST database...
9.
Keen T, Morris A, Inglehearn C
J Med Genet . 1997 Feb; 34(2):130-2. PMID: 9039989
The involvement of genes with expanded tracts of (CAG)n in some neurodegenerative diseases is well established. Whether genes containing these motifs could also have a role in degenerative diseases affecting...
10.
Reynolds P, Powlesland R, Keen T, Inglehearn C, Cunningham A, Green E, et al.
Genes Chromosomes Cancer . 1996 Nov; 17(3):151-5. PMID: 8946193
Cytogenetic analysis of predisposition syndromes has played a critical role in the elucidation of the genetics of Wilms' tumor (WT). Therefore, we became interested in a patient who presented with...