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T I Ng

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Articles 11
Citations 262
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Recent Articles
1.
Ng T, Shi Y, Huffaker H, Kati W, Liu Y, Chen C, et al.
Antimicrob Agents Chemother . 2001 May; 45(6):1629-36. PMID: 11353604
(R)-9-[4-Hydroxy-2-(hydroxymethy)butyl]guanine (H2G) is a potent and selective inhibitor of herpesvirus replication. It is a nucleoside analog, and its triphosphate derivative (H2G-TP) is a competitive inhibitor of herpesvirus DNA polymerases. In...
2.
Talarico C, Burnette T, Miller W, Smith S, Davis M, STANAT S, et al.
Antimicrob Agents Chemother . 1999 Aug; 43(8):1941-6. PMID: 10428917
Acyclovir (ACV) has shown efficacy in the prophylactic suppression of human cytomegalovirus (HCMV) reactivation in immunocompromised renal transplant patients without the toxicity associated with ganciclovir (GCV). The HCMV UL97 gene...
3.
Ang S, Cheong K, Ng T
Anaesth Intensive Care . 1999 Apr; 27(2):175-8. PMID: 10212715
We assessed the effect of two different doses of alfentanil (5 and 10 micrograms.kg-1) on the conditions for laryngeal mask airway insertion in ASA 1 and 2 patients who received...
4.
Ng T, Ogle W, Roizman B
Virology . 1998 Feb; 241(1):37-48. PMID: 9454715
Herpes simplex virus 1 encodes a Fc receptor consisting of glycoproteins E (gE) and I (gI) and two protein kinases specified by UL13 and US3, respectively. We report the following:...
5.
Ogle W, Ng T, Carter K, Roizman B
Virology . 1997 Sep; 235(2):406-13. PMID: 9281521
The herpes simplex virus infected-cell protein 0 (ICP0) acts as a promiscuous transactivator of genes introduced into eukaryotic cells by transfection or infection. The protein is highly posttranslationally modified by...
6.
Ng T, Chang Y, Roizman B
Virology . 1997 Aug; 234(2):226-34. PMID: 9268153
The U(L)41 protein of herpes simplex virus 1 (HSV-1) is packaged into virions, and in newly infected cells the protein mediates indiscriminate degradation of mRNA, which causes a shutoff of...
7.
Ng T, Talarico C, Burnette T, Biron K, Roizman B
Virology . 1996 Nov; 225(2):347-58. PMID: 8918921
The predicted amino acid sequence of the human cytomegalovirus U(L)97 protein bears partial homology to the herpes simplex virus 1 U(L)13 protein, especially in regions that are homologous to conserved...
8.
Ng T, Keenan L, Kinchington P, Grose C
J Virol . 1994 Mar; 68(3):1350-9. PMID: 8107200
Varicella-zoster virus (VZV) encodes within its unique long region a gene product with protein kinase motifs. In a previous study, we demonstrated that immunoprecipitated VZV open reading frame (ORF) 47...
9.
Ng T, Grose C
Virology . 1992 Nov; 191(1):9-18. PMID: 1329339
Varicella-zoster virus (VZV) ORF 47 lies in the unique long region of the VZV genome. Sequence homology studies have demonstrated that gene 47 possessed conserved protein kinase motifs. In this...
10.
Ng T, Lim E, Tweed W, Arulkumaran S
Ann Acad Med Singap . 1992 Nov; 21(6):804-6. PMID: 1295421
A five-year retrospective study of obstetric admissions to the Surgical Intensive Care Unit (SICU) in the National University Hospital, Singapore was carried out with the aim of determining the incidence,...