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T I Gudz

Explore the profile of T I Gudz including associated specialties, affiliations and a list of published articles. Areas
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Articles 43
Citations 508
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Recent Articles
1.
Kuryshev Y, Wible B, Gudz T, Ramirez A, Brown A
Am J Physiol Cell Physiol . 2001 Jun; 281(1):C290-9. PMID: 11401852
KChAP and voltage-dependent K+ (Kv) beta-subunits are two different types of cytoplasmic proteins that interact with Kv channels. KChAP acts as a chaperone for Kv2.1 and Kv4.3 channels. It also...
2.
Lesnefsky E, Gudz T, Migita C, Hassan M, Turkaly P, Hoppel C
Arch Biochem Biophys . 2001 May; 385(1):117-28. PMID: 11361007
The aging heart sustains greater injury during ischemia and reperfusion compared to adult hearts. Aging decreases oxidative function in interfibrillar mitochondria (IFM) that reside among the myofibers, while subsarcolemmal mitochondria...
3.
Lesnefsky E, Gudz T, Moghaddas S, Migita C, Turkaly P, Hoppel C
J Mol Cell Cardiol . 2001 Jan; 33(1):37-47. PMID: 11133221
Aging alters cardiac physiology and structure and enhances damage during ischemia and reperfusion. Aging selectively decreases the rate of oxidative phosphorylation in the interfibrillar population of cardiac mitochondria (IFM) located...
4.
Kuryshev Y, Gudz T, Brown A, Wible B
Am J Physiol Cell Physiol . 2000 May; 278(5):C931-41. PMID: 10794667
The concept of chaperones for K(+) channels is new. Recently, we discovered a novel molecular chaperone, KChAP, which increased total Kv2.1 protein and functional channels in Xenopus oocytes through a...
5.
Gudz T, Tserng K, Hoppel C
J Biol Chem . 1997 Sep; 272(39):24154-8. PMID: 9305864
Ceramide is a lipid second messenger that mediates the effects of tumor necrosis factor alpha and other agents on cell growth and differentiation. Ceramide is believed to act via activation...
6.
Novgorodov S, Gudz T
J Bioenerg Biomembr . 1996 Apr; 28(2):139-46. PMID: 9132412
Prooxidants induce release of Ca2+ from mitochondria through the giant solute pore in the mitochondrial inner membrane. However, under appropriate conditions prooxidants can induce Ca2+ release without inducing a nonspecific...
7.
Pfeiffer D, Gudz T, Novgorodov S, Erdahl W
J Biol Chem . 1995 Mar; 270(9):4923-32. PMID: 7876267
Mastoparan facilitates opening of the mitochondrial permeability transition pore through an apparent bimodal mechanism of action. In the submicromolar concentration range, the action of mastoparan is dependent upon the medium...
8.
Novgorodov S, Gudz T, Brierley G, Pfeiffer D
Arch Biochem Biophys . 1994 Jun; 311(2):219-28. PMID: 8203884
Regulation of the mitochondrial permeability transition pore has been investigated following the release of matrix solutes which normally participate in pore regulation. Under these conditions, neither cyclosporin A nor ADP...
9.
Gudz T, Pandelova I, Novgorodov S
Radiat Res . 1994 Apr; 138(1):114-20. PMID: 8146290
The effect of X irradiation on the respiration of rat thymocytes was studied. An increase in the rate of O2 uptake was observed 1 h after cells were irradiated with...
10.
Novgorodov S, Gudz T, Milgrom Y, Brierley G
J Biol Chem . 1992 Aug; 267(23):16274-82. PMID: 1644813
Heart mitochondria respiring in a sucrose medium containing P(i) show a permeability transition when challenged with Ca2+ and an oxidant such as cumene hydroperoxide. The transition results from the opening...