Ensembl 2004

Overview

Journal Nucleic Acids Res

Publisher Oxford University Press

Specialty Biochemistry

Date 2003 Dec 19

PMID 14681459

Citations 81

Authors

E Birney

D Andrews

P Bevan

M Caccamo

G Cameron

Y Chen

L Clarke

G Coates

T Cox

J Cuff

V Curwen

T Cutts

T Down

R Durbin

E Eyras

X M Fernandez-Suarez

P Gane

B Gibbins

J Gilbert

M Hammond

H Hotz

V Iyer

A Kahari

K Jekosch

A Kasprzyk

D Keefe

S Keenan

H Lehvaslaiho

G McVicker

C Melsopp

P Meidl

E Mongin

R Pettett

S Potter

G Proctor

M Rae

S Searle

G Slater

D Smedley

J Smith

W Spooner

A Stabenau

J STALKER

R Storey

A Ureta-Vidal

C Woodwark

M Clamp

T Hubbard

Affiliations

Soon will be listed here.

Abstract

The Ensembl (http://www.ensembl.org/) database project provides a bioinformatics framework to organize biology around the sequences of large genomes. It is a comprehensive and integrated source of annotation of large genome sequences, available via interactive website, web services or flat files. As well as being one of the leading sources of genome annotation, Ensembl is an open source software engineering project to develop a portable system able to handle very large genomes and associated requirements. The facilities of the system range from sequence analysis to data storage and visualization and installations exist around the world both in companies and at academic sites. With a total of nine genome sequences available from Ensembl and more genomes to follow, recent developments have focused mainly on closer integration between genomes and external data.

Citing Articles

Reactome graph database: Efficient access to complex pathway data.

Fabregat A, Korninger F, Viteri G, Sidiropoulos K, Marin-Garcia P, Ping P PLoS Comput Biol. 2018; 14(1):e1005968.

PMID: 29377902 PMC: 5805351. DOI: 10.1371/journal.pcbi.1005968.

Metabolic and chaperone gene loss marks the origin of animals: evidence for Hsp104 and Hsp78 chaperones sharing mitochondrial enzymes as clients.

Erives A, Fassler J PLoS One. 2015; 10(2):e0117192.

PMID: 25710177 PMC: 4339202. DOI: 10.1371/journal.pone.0117192.

A novel splice variant of XIAP-associated factor 1 (XAF1) is expressed in peripheral blood containing gastric cancer-derived circulating tumor cells.

Hatakeyama K, Yamakawa Y, Fukuda Y, Ohshima K, Wakabayashi-Nakao K, Sakura N Gastric Cancer. 2014; 18(4):751-61.

PMID: 25216542 DOI: 10.1007/s10120-014-0426-3.

Discovery of a metabolic alternative to the classical mevalonate pathway.

Dellas N, Thomas S, Manning G, Noel J Elife. 2013; 2:e00672.

PMID: 24327557 PMC: 3857490. DOI: 10.7554/eLife.00672.

Robust demographic inference from genomic and SNP data.

Excoffier L, Dupanloup I, Huerta-Sanchez E, Sousa V, Foll M PLoS Genet. 2013; 9(10):e1003905.

PMID: 24204310 PMC: 3812088. DOI: 10.1371/journal.pgen.1003905.

References

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