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T Hermiston

Explore the profile of T Hermiston including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 397
Followers 0
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Recent Articles
1.
Beier R, Hermiston T, Mumberg D
Gene Ther . 2012 Feb; 20(1):102-11. PMID: 22357510
Newcastle disease virus (NDV) is an oncolytic paramyxovirus with a nonsegmented single-stranded RNA genome. In this report, a recombinant oncolytic NDV was passaged in human tumor xenografts and reisolated and...
2.
Bauzon M, Jin F, Kretschmer P, Hermiston T
Gene Ther . 2009 May; 16(9):1169-74. PMID: 19458647
We have generated a novel oncolytic Adenovirus (Ad), ColoAd1, with significantly increased potency ( approximately 100-fold) relative to its parent viruses, Ad11p and Ad3, or to the clinically tested oncolytic...
3.
Kuhn I, LARSEN B, Gross C, Hermiston T
Gene Ther . 2006 Oct; 14(2):180-4. PMID: 17024108
Accurate adenovirus (Ad) quantification requires labor- and time-intensive viral stock purification. While crude viral lysates can be titered by plaque assay, this cell-based assay is neither rapid nor accurate. Consequently,...
4.
Green N, Herbert C, Hale S, Hale A, Mautner V, Harkins R, et al.
Gene Ther . 2004 Jun; 11(16):1256-63. PMID: 15215884
Systemic delivery of adenoviral vectors is a major goal in cancer gene therapy, but is currently prohibited by rapid hepatic uptake of virus following intravenous injection with levels of viable...
5.
Hawkins L, Hermiston T
Gene Ther . 2001 Aug; 8(15):1142-8. PMID: 11509944
Successful therapies for cancer need to deal with the complexity associated with the human tumor. Studies of tumor and viral biology have progressed to a point where replicating viruses are...
6.
Shen Y, KITZES G, Nye J, Fattaey A, Hermiston T
J Virol . 2001 Apr; 75(9):4297-307. PMID: 11287579
The E1B-55K protein plays an important role during human adenovirus type 5 productive infection. In the early phase of the viral infection, E1B-55K binds to and inactivates the tumor suppressor...
7.
Heise C, Hermiston T, Johnson L, Brooks G, Sampson-Johannes A, Williams A, et al.
Nat Med . 2000 Oct; 6(10):1134-9. PMID: 11017145
Replication-selective oncolytic viruses constitute a rapidly evolving and new treatment platform for cancer. Gene-deleted viruses have been engineered for tumor selectivity, but these gene deletions also reduce the anti-cancer potency...
8.
Hermiston T
J Clin Invest . 2000 May; 105(9):1169-72. PMID: 10791988
No abstract available.
9.
Kirn D, Hermiston T
Nat Med . 1999 Sep; 5(9):991-2. PMID: 10470071
No abstract available.
10.
Kirn D, Hermiston T, McCormick F
Nat Med . 1998 Dec; 4(12):1341-2. PMID: 9846551
No abstract available.