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T E Hardingham

Explore the profile of T E Hardingham including associated specialties, affiliations and a list of published articles. Areas
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Articles 93
Citations 2032
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Recent Articles
1.
Ajekigbe B, Cheung K, Xu Y, Skelton A, Panagiotopoulos A, Soul J, et al.
Osteoarthritis Cartilage . 2019 Jan; 27(4):694-702. PMID: 30611906
Objective: Long intergenic non-coding RNAs (lincRNAs) are emerging as key regulators in gene expression; however, little is known about the lincRNA expression changes that occur in osteoarthritis (OA). Here we...
2.
Dunn S, Soul J, Anand S, Schwartz J, Boot-Handford R, Hardingham T
Osteoarthritis Cartilage . 2016 Mar; 24(8):1431-40. PMID: 26973327
Objectives: Joint degeneration in osteoarthritis (OA) is characterised by damage and loss of articular cartilage. The pattern of loss is consistent with damage occurring only where the mechanical loading is...
3.
Hardingham T
Ann Rheum Dis . 2014 Oct; 34 Suppl 2:Suppl 52-4. PMID: 25330579
No abstract available.
4.
Hardingham T, Muir H
Ann Rheum Dis . 2014 Oct; 34 Suppl 2:Suppl 26-8. PMID: 25330573
No abstract available.
5.
Khan W, Adesida A, Tew S, Longo U, Hardingham T
Cell Prolif . 2012 Jan; 45(2):111-20. PMID: 22260253
Background: Mesenchymal stem cells are able to undergo adipogenic differentiation and present a possible alternative cell source for regeneration and replacement of adipose tissue. The human infrapatellar fat pad is...
6.
Hardingham T
Ups J Med Sci . 2010 Jan; 82(2):67-8. PMID: 20078278
No abstract available.
7.
Khan W, Adesida A, Tew S, Andrew J, Hardingham T
Injury . 2008 Dec; 40(2):150-7. PMID: 19070850
Some clinical settings are deficient in osteogenic progenitors, e.g. atrophic nonunited fractures, large bone defects, and regions of scarring and osteonecrosis. These benefit from the additional use of bone marrow-derived...
8.
Papagiannopoulos A, Waigh T, Hardingham T
Faraday Discuss . 2008 Dec; 139:337-57. PMID: 19049005
Particle tracking microrheology with a fast digital camera allowed the slow and intermediate time regimes (10(-4)-10(1) s) of the linear viscoelasticity of giant aggrecan proteoglycans to be mapped. Combined with...
9.
Goodstone N, Hardingham T
Rheumatology (Oxford) . 2002 Aug; 41(8):883-91. PMID: 12154205
Objective: To compare the time- and concentration-dependent effects of tumour necrosis factor alpha (TNF-alpha) and interleukin 1beta (IL-1beta) on the induction of nitric oxide synthase (NOS), the production of nitric...
10.
Kolettas E, Muir H, Barrett J, Hardingham T
Rheumatology (Oxford) . 2001 Oct; 40(10):1146-56. PMID: 11600745
Objective: To investigate the effects of culture conditions, serum and specific cytokines such as insulin-like growth factor (IGF) 1 and interleukin (IL) 1alpha on phenotype and cell survival in cultures...