T B Shea
Overview
Explore the profile of T B Shea including associated specialties, affiliations and a list of published articles.
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123
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1144
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Recent Articles
1.
Dhitavat S, Rivera E, Rogers E, Shea T
J Alzheimers Dis
. 2012 Mar;
3(6):525-9.
PMID: 22387694
Exposure of neurons to amyloid-beta (Abeta) is accompanied by a cascade of oxidative damage that initiates with lipid peroxidation followed by subsequent generation of cytosolic free radicals and reactive oxygen...
2.
Chan A, Ortiz D, Rogers E, Shea T
J Nutr Health Aging
. 2011 Mar;
15(3):221-5.
PMID: 21369671
Folate insufficiency promotes developmental as well as age-related disorders of the nervous system. The C677T variant of 5',10' methylene tetrahydrofolate reductase (MTHFR; which utilizes folate to regenerate methionine from homocysteine)...
3.
Chan A, Remington R, Kotyla E, Lepore A, Zemianek J, Shea T
J Nutr Health Aging
. 2010 Mar;
14(3):224-30.
PMID: 20191258
Adults of both genders without dementia consumed a nutriceutical formulation ("NF," consisting of folic acid, B12, Vitamin E, S-adenosylmethionine, N-acetyl cysteine and Acetyl-L-carnitine), previously shown to improve cognitive performance in...
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Chan A, Tchantchou F, Graves V, Rozen R, Shea T
J Nutr Health Aging
. 2008 Apr;
12(4):252-61.
PMID: 18373034
Folate deficiency has been associated with age-related neurodegeneration. One direct consequence of folate deficiency is a decline in the major methyl donor, S-adenosyl methionine (SAM). We demonstrate herein that pro-oxidant...
7.
Tchantchou F, Graves M, Ortiz D, Chan A, Rogers E, Shea T
J Nutr Health Aging
. 2006 Dec;
10(6):541-4.
PMID: 17183426
Clinical manifestation of Alzheimer's disease may depend upon interaction among its risk factors. Apolipoprotein E-deficient mice undergo oxidative damage and cognitive impairment when deprived of folate. We demonstrate herein that...
8.
Tchantchou F, Graves M, Ortiz D, Rogers E, Shea T
J Nutr Health Aging
. 2004 Nov;
8(6):492-6.
PMID: 15543422
Increased oxidative stress, which can arise from dietary, environmental and/or genetic sources, contributes to the decline in cognitive performance during normal aging and in neurodegenerative conditions such as Alzheimer's disease....
9.
Rogers E, Milhalik S, Orthiz D, Shea T
J Nutr Health Aging
. 2004 Feb;
8(2):92-7.
PMID: 14978604
Increased oxidative stress contributes to the decline in cognitive performance during normal aging and in neurodegenerative conditions such as Alzheimer s disease. Dietary supplementation with fruits and vegetables that are...
10.
Shea T, Ekinci F, Ortiz D, WILSON T, Nicolosi R
J Nutr Health Aging
. 2003 Aug;
7(4):252-5.
PMID: 12917750
Oxidative stress is a pivotal factor in neuronal degeneration including that induced by exposure to amyloid-beta (Abeta). Treatment with antioxidants such as vitamin E can alleviate Abeta neurotoxicity. However, vitamin...