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T B Sculley

Explore the profile of T B Sculley including associated specialties, affiliations and a list of published articles. Areas
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Articles 63
Citations 925
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Recent Articles
1.
Blood A, Edwards C, Ishii H, Pat B, Bryson G, Sculley T, et al.
Arch Virol . 2004 Jan; 149(2):289-302. PMID: 14745596
Epstein-Barr virus (EBV)-infected B cell lymphomas are resistant to apoptosis during cancer development and treatment with therapies. The molecular controls that determine why EBV infection causes apoptosis resistance need further...
2.
Kienzle N, Buck M, Greco S, Krauer K, Sculley T
J Virol . 1999 Sep; 73(10):8902-6. PMID: 10482651
The cellular localization of the Epstein-Barr virus-encoded RK-BARF0 protein was analyzed by fluorescence microscopy and immunoblotting. The recombinant RK-BARF0 protein was found to be tightly bound to nuclear structures, whereas...
3.
Kienzle N, Sculley T, Greco S, Khanna R
J Immunol . 1999 Jun; 162(12):6963-6. PMID: 10358134
Persistent viruses have developed potent strategies to overcome host immune defenses. In particular, viral interference with Ag presentation by HLA class I molecules can effectively impair the host's CTL function....
4.
Buck M, Cross S, Krauer K, Kienzle N, Sculley T
J Gen Virol . 1999 Mar; 80 ( Pt 2):441-445. PMID: 10073706
In this study replication of A-type and B-type Epstein-Barr virus (EBV) strains has been assessed. A-type and B-type type lymphoblastoid cell lines (LCLs) were established by infecting B lymphocytes, isolated...
5.
Kienzle N, Young D, Liaskou D, Buck M, Greco S, Sculley T
J Virol . 1999 Jan; 73(2):1195-204. PMID: 9882321
The nuclear antigen 3 family genes (EBNA-3, EBNA-4, and EBNA-6) of Epstein-Barr virus (EBV) are important for EBV-induced immortalization and survival of B lymphocytes. However, little is known about how...
6.
Kienzle N, Sculley T, Poulsen L, Buck M, Cross S, Raab-Traub N, et al.
J Virol . 1998 Jul; 72(8):6614-20. PMID: 9658107
The Epstein-Barr virus (EBV)-encoded BARF0 open reading frame gene products are consistently expressed in EBV-positive Burkitt's lymphoma (BL) cell lines, nasopharyngeal carcinoma cell lines, and lymphoblastoid cell lines (LCLs). Here...
7.
Kienzle N, Cross S, Young D, Misko I, Sculley T, Abrams C
Blood . 1997 May; 89(9):3488-90. PMID: 9129059
No abstract available.
8.
Fries K, Sculley T, Webster-Cyriaque J, Rajadurai P, Sadler R, Raab-Traub N
J Virol . 1997 Apr; 71(4):2765-71. PMID: 9060630
An unusual set of 3' coterminal, spliced mRNAs transcribed through the BamHI A fragment have been previously identified in nasopharyngeal carcinoma (NPC) tissues. These RNAs have also been detected at...
9.
Krauer K, Kienzle N, Young D, Sculley T
Virology . 1996 Dec; 226(2):346-53. PMID: 8955054
The Epstein-Barr nuclear antigen (EBNA)-3 and EBNA-4 proteins are thought to act as transcriptional transactivators. The yeast two-hybrid system and coimmunoprecipitation were used to demonstrate that EBNA-3 and -4 associate...
10.
Kerr B, Kienzle N, Burrows J, Cross S, Silins S, Buck M, et al.
J Virol . 1996 Dec; 70(12):8858-64. PMID: 8971014
Persistent Epstein-Barr virus (EBV) infection is primarily controlled by HLA class I-restricted memory cytotoxic T-cell (CTL) responses which can be reactivated in vitro by stimulation of peripheral blood lymphocytes with...