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T A Ferguson

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21.
Brunner T, Yoo N, Griffith T, Ferguson T, Green D
Behring Inst Mitt . 1996 Oct; (97):161-74. PMID: 8950474
Peripheral deletion of activated T cells has an important function in the regulation of the extent of an immune response. Upon restimulation through the T cell receptor previously stimulated cells...
22.
Griffith T, Yu X, Herndon J, Green D, Ferguson T
Immunity . 1996 Jul; 5(1):7-16. PMID: 8758890
We examined the relationship between cell death and tolerance induction following antigen injection into the anterior chamber of the eye. Our data show that when inflammatory cells undergo apoptosis following...
23.
Shornick L, DE TOGNI P, Mariathasan S, Goellner J, Strauss-Schoenberger J, Karr R, et al.
J Exp Med . 1996 Apr; 183(4):1427-36. PMID: 8666901
Mice rendered deficient in IL-1 beta by gene targeting in embryonic stem cells develop and grow normally in a protected laboratory environment. Endotoxin-stimulated peritoneal macrophages from IL-1beta-deficient mice showed normal...
24.
Griffith T, Brunner T, Fletcher S, Green D, Ferguson T
Science . 1995 Nov; 270(5239):1189-92. PMID: 7502042
The eye is a privileged site that cannot tolerate destructive inflammatory responses. Inflammatory cells entering the anterior chamber of the eye in response to viral infection underwent apoptosis that was...
25.
Griffith T, Herndon J, Lima J, Kahn M, Ferguson T
Int Immunol . 1995 Oct; 7(10):1617-25. PMID: 8562507
Injection of antigen into the anterior chamber (AC) of the eye results in the induction of immune deviation in which antibody production is activated and delayed-type hypersensitivity (DTH) is inhibited....
26.
Ferguson T, Fletcher S, Herndon J, Griffith T
J Immunol . 1995 Aug; 155(4):1746-56. PMID: 7543531
Ag presentation via the anterior chamber of the eye results in a form of immune deviation termed anterior chamber-associated immune deviation (ACAID). The hallmarks of this response are the suppression...
27.
Ferguson T, Herndon J
Invest Ophthalmol Vis Sci . 1994 Jun; 35(7):3085-93. PMID: 8206727
Purpose: To examine conditions that determine the nature of the blood-borne, ACAID-inducing signal produced after intracameral injection of antigen. Methods: Balb/c mice were splenectomized, rested, and injected in the anterior...
28.
Ferguson T, Dube P, Griffith T
J Exp Med . 1994 May; 179(5):1597-604. PMID: 8163939
Contact hypersensitivity (CHS) responses require the participation of T cells, along with a variety of cytokines and adhesion molecules. In the classical CHS, antigen-specific T cells are recruited to a...
29.
Ferguson T, Herndon J, Dube P
Invest Ophthalmol Vis Sci . 1994 Apr; 35(5):2643-51. PMID: 8163352
Purpose: Interleukin-1 and tumor necrosis factor (TNF) alpha are proinflammatory cytokines and crucial mediators in many aspects of immunity. In this study, their role in anterior chamber-associated immune deviation (ACAID)...
30.
Goldberg M, Ferguson T, Pepose J
Ophthalmology . 1994 Jan; 101(1):161-8. PMID: 8302550
Purpose: The expression of cellular adhesion molecules in 31 penetrating keratoplasty specimens from a broad range of corneal inflammatory diseases was studied using monoclonal antibodies and an immunoperoxidase technique. Methods:...