T-C Wu
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Explore the profile of T-C Wu including associated specialties, affiliations and a list of published articles.
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217
Citations
5235
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Recent Articles
11.
Peng S, Xing D, Ferrall L, Tsai Y, Roden R, Hung C, et al.
mBio
. 2022 Jan;
13(1):e0325221.
PMID: 35089069
Human papillomavirus (HPV)-associated head and neck squamous cell carcinoma (HNSCC) is a growing global health problem. HPV16 has been attributed to a majority of HPV-associated HNSCCs. In order to test...
12.
Feng P, Wang X, Ferrall L, Wu T, Hung C
J Immunol Res
. 2022 Jan;
2022:9054569.
PMID: 35028321
Tumor antigen-specific T cell function is limited by immune tolerance in the tumor microenvironment. In the tumor microenvironment, tumor cells upregulate PD-L1 expression to promote T cell exhaustion by PD-1/PD-L1...
13.
MacDonald A, Lam B, Lin J, Ferrall L, Kung Y, Tsai Y, et al.
Front Immunol
. 2021 Nov;
12:755995.
PMID: 34804041
The phospholipid phosphatidylserine (PS) is naturally maintained on the cytoplasmic side of the plasma membrane. Independent of apoptosis, PS is redistributed to the surface of CD8 T cells in response...
14.
MacDonald A, Wu T, Hung C
J Immunol Res
. 2021 Nov;
2021:7855808.
PMID: 34790830
Interleukin 2 (IL-2) plays a fundamental role in both immune activation and tolerance and has revolutionized the field of cancer immunotherapy since its discovery. The ability of IL-2 to mediate...
15.
Henkle T, Lam B, Kung Y, Lin J, Tseng S, Ferrall L, et al.
Cancer Res
. 2021 Jul;
81(17):4560-4569.
PMID: 34215618
Current preclinical models for cervical cancer lack important clinical and pathologic features. To improve upon these models, we aimed to develop a novel, spontaneous HPV16-expressing carcinoma model that captures major...
16.
Ferrall L, Lin K, Roden R, Hung C, Wu T
Clin Cancer Res
. 2021 Apr;
27(18):4953-4973.
PMID: 33888488
It is a sad fact that despite being almost completely preventable through human papillomavirus (HPV) vaccination and screening, cervical cancer remains the fourth most common cancer to affect women worldwide....
17.
Peng S, Ferrall L, Gaillard S, Wang C, Chi W, Huang C, et al.
mBio
. 2021 Jan;
12(1).
PMID: 33468698
Immunotherapy for cervical cancer should target high-risk human papillomavirus types 16 and 18, which cause 50% and 20% of cervical cancers, respectively. Here, we describe the construction and characterization of...
18.
Li Y, Chi W, Su J, Ferrall L, Hung C, Wu T
J Biomed Sci
. 2020 Dec;
27(1):104.
PMID: 33341119
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a new type of coronavirus that causes the Coronavirus Disease 2019 (COVID-19), which has been the most challenging pandemic in this century....
19.
Farmer E, Cheng M, Hung C, Wu T
Recent Results Cancer Res
. 2020 Nov;
217:157-195.
PMID: 33200366
Human papillomavirus (HPV) is the most common sexually transmitted infection, currently affecting close to 80 million Americans. Importantly, HPV infection is recognized as the etiologic factor for numerous cancers, including...
20.
Peng S, Tan M, Li Y, Cheng M, Farmer E, Ferrall L, et al.
Cancer Immunol Immunother
. 2020 Oct;
70(4):1049-1062.
PMID: 33108473
Introduction: The human papillomavirus (HPV) encoded oncoproteins E6 and E7 are constitutively expressed in HPV-associated cancers, making them logical therapeutic targets. Intramuscular immunization of patients with HPV16 L2E7E6 fusion protein...