Sylvia K Plevritis
Overview
Explore the profile of Sylvia K Plevritis including associated specialties, affiliations and a list of published articles.
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122
Citations
9613
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Recent Articles
11.
Karacosta L, Pancirer D, Preiss J, Benson J, Trope W, Shrager J, et al.
Sci Rep
. 2023 Dec;
13(1):21781.
PMID: 38065965
Malignant pleural effusions (MPEs) can be utilized as liquid biopsy for phenotyping malignant cells and for precision immunotherapy, yet MPEs are inadequately studied at the single-cell proteomic level. Here we...
12.
Brennan K, Espin-Perez A, Chang S, Bedi N, Saumyaa S, Shin J, et al.
Genome Med
. 2023 Nov;
15(1):98.
PMID: 37978395
Background: The prognosis for patients with head and neck cancer (HNC) is poor and has improved little in recent decades, partially due to lack of therapeutic options. To identify effective...
13.
Bouchard G, Zhang W, Li I, Ilerten I, Bhattacharya A, Li Y, et al.
bioRxiv
. 2023 Sep;
PMID: 37745466
Computational frameworks to quantify and compare microenvironment spatial features of in-vitro patient-derived models and clinical specimens are needed. Here, we acquired and analysed multiplexed immunofluorescence images of human lung adenocarcinoma...
14.
Kaiser A, Gatto A, Hanson K, Zhao R, Raj N, Ozawa M, et al.
Nature
. 2023 Jul;
619(7971):851-859.
PMID: 37468633
Lung cancer is the leading cause of cancer deaths worldwide. Mutations in the tumour suppressor gene TP53 occur in 50% of lung adenocarcinomas (LUADs) and are linked to poor prognosis,...
15.
Hickey J, Becker W, Nevins S, Horning A, Perez A, Zhu C, et al.
Nature
. 2023 Jul;
619(7970):572-584.
PMID: 37468586
The intestine is a complex organ that promotes digestion, extracts nutrients, participates in immune surveillance, maintains critical symbiotic relationships with microbiota and affects overall health. The intesting has a length...
16.
Toumazis I, Cao P, de Nijs K, Bastani M, Munshi V, Hemmati M, et al.
Ann Intern Med
. 2023 Feb;
176(3):320-332.
PMID: 36745885
Background: In their 2021 lung cancer screening recommendation update, the U.S. Preventive Services Task Force (USPSTF) evaluated strategies that select people based on their personal lung cancer risk (risk model-based...
17.
Good Z, Spiegel J, Sahaf B, Malipatlolla M, Ehlinger Z, Kurra S, et al.
Nat Med
. 2022 Sep;
28(9):1860-1871.
PMID: 36097223
Approximately 60% of patients with large B cell lymphoma treated with chimeric antigen receptor (CAR) T cell therapies targeting CD19 experience disease progression, and neurotoxicity remains a challenge. Biomarkers associated...
18.
Zhang W, Li I, Reticker-Flynn N, Good Z, Chang S, Samusik N, et al.
Nat Methods
. 2022 Jun;
19(6):759-769.
PMID: 35654951
Advances in multiplexed in situ imaging are revealing important insights in spatial biology. However, cell type identification remains a major challenge in imaging analysis, with most existing methods involving substantial...
19.
Reticker-Flynn N, Zhang W, Belk J, Basto P, Escalante N, Pilarowski G, et al.
Cell
. 2022 May;
185(11):1924-1942.e23.
PMID: 35525247
For many solid malignancies, lymph node (LN) involvement represents a harbinger of distant metastatic disease and, therefore, an important prognostic factor. Beyond its utility as a biomarker, whether and how...
20.
Yu A, Li Y, Li I, Ozawa M, Yeh C, Chiou A, et al.
Sci Adv
. 2022 Mar;
8(11):eabi4757.
PMID: 35302849
Cellular cross-talk in tissue microenvironments is fundamental to normal and pathological biological processes. Global assessment of cell-cell interactions (CCIs) is not yet technically feasible, but computational efforts to reconstruct these...