Sylvia E J Fischer
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Explore the profile of Sylvia E J Fischer including associated specialties, affiliations and a list of published articles.
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22
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769
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Recent Articles
1.
Vassallo B, Scheidel N, Fischer S, Kim D
Elife
. 2024 Jul;
12.
PMID: 38990923
The microbiota is a key determinant of the physiology and immunity of animal hosts. The factors governing the transmissibility of viruses between susceptible hosts are incompletely understood. Bacteria serve as...
2.
Lee H, Boor S, Hilbert Z, Meisel J, Park J, Wang Y, et al.
Sci Adv
. 2024 Jun;
10(24):eadk9481.
PMID: 38865452
The molecular mechanisms underlying diversity in animal behavior are not well understood. A major experimental challenge is determining the contribution of genetic variants that affect neuronal gene expression to differences...
3.
Lee H, Boor S, Hilbert Z, Meisel J, Park J, Wang Y, et al.
bioRxiv
. 2023 Sep;
PMID: 37745484
The molecular mechanisms underlying diversity in animal behavior are not well understood. A major experimental challenge is determining the contribution of genetic variants that affect neuronal gene expression to differences...
4.
Vassallo B, Scheidel N, Fischer S, Kim D
bioRxiv
. 2023 Sep;
PMID: 37732241
The microbiota is a key determinant of the physiology and immunity of animal hosts. The factors governing the transmissibility of viruses between susceptible hosts are incompletely understood. Bacteria serve as...
5.
Braun M, Shoshani S, Teixeira J, Mellul Shtern A, Miller M, Granot Z, et al.
iScience
. 2022 May;
25(5):104246.
PMID: 35494247
Nucleotide repeat expansions are a hallmark of over 40 neurodegenerative diseases and cause RNA toxicity and multisystemic symptoms that worsen with age. Through an unclear mechanism, RNA toxicity can trigger...
6.
Wasson J, Harris G, Keppler-Ross S, Brock T, Dar A, Butcher R, et al.
Sci Adv
. 2021 Aug;
7(34).
PMID: 34417172
Mothers contribute cytoplasmic components to their progeny in a process called maternal provisioning. Provisioning is influenced by the parental environment, but the molecular pathways that transmit environmental cues between generations...
7.
Fischer S, Ruvkun G
Proc Natl Acad Sci U S A
. 2020 Mar;
117(11):5987-5996.
PMID: 32123111
Endogenous retroviruses and long terminal repeat (LTR) retrotransposons are mobile genetic elements that are closely related to retroviruses. Desilenced endogenous retroviruses are associated with human autoimmune disorders and neurodegenerative diseases....
8.
Newman M, Ji F, Fischer S, Anselmo A, Sadreyev R, Ruvkun G
Genes Dev
. 2018 May;
32(9-10):670-681.
PMID: 29739806
RNAi pathways detect and silence foreign nucleic acids such as viruses as well as endogenous genes in many species. The phylogenetic profile across eukaryotes of proteins that mediate key steps...
9.
Fischer S
Curr Protoc Mol Biol
. 2015 Oct;
112:26.1.1-26.1.5.
PMID: 26423588
RNA interference (RNAi) and microRNA-mediated silencing cause sequence-specific silencing of target genes. This overview will give a brief description of how RNAi and microRNAs were discovered, how small RNAs silence...
10.
Billi A, Fischer S, Kim J
WormBook
. 2014 May;
:1-49.
PMID: 24816713
In addition to several hundred microRNAs, C. elegans produces thousands of other small RNAs targeting coding genes, pseudogenes, transposons, and other noncoding RNAs. Here we review what is currently known...