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Sylvain J Le Marchand

Explore the profile of Sylvain J Le Marchand including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 759
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11.
Le Marchand S, Piston D
J Biol Chem . 2010 Mar; 285(19):14389-98. PMID: 20231269
Glucagon is released from alpha-cells present in intact pancreatic islets at glucose concentrations below 4 mm, whereas higher glucose levels inhibit its secretion. The mechanisms underlying the suppression of alpha-cell...
12.
Hilliard F, Steele D, Laver D, Yang Z, Le Marchand S, Chopra N, et al.
J Mol Cell Cardiol . 2009 Oct; 48(2):293-301. PMID: 19835880
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is linked to mutations in the cardiac ryanodine receptor (RyR2) or calsequestrin. We recently found that the drug flecainide inhibits RyR2 channels and prevents CPVT...