Syed Mian
Overview
Explore the profile of Syed Mian including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
6
Citations
249
Followers
0
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Recent Articles
1.
Kizilors A, Crisa E, Lea N, Passera R, Mian S, Anwar J, et al.
Lancet Haematol
. 2019 May;
6(5):e276-e284.
PMID: 31036317
Background: Kinase domain mutations in BCR-ABL1 are associated with resistance to tyrosine kinase inhibitors in patients with chronic myeloid leukaemia. Next-generation sequencing (NGS) allows detection of low-level kinase domain mutations,...
2.
Di Tullio A, Rouault-Pierre K, Abarrategi A, Mian S, Grey W, Gribben J, et al.
Nat Commun
. 2017 Nov;
8(1):1679.
PMID: 29162833
Cytarabine (AraC) represents the most effective single agent treatment for AML. Nevertheless, overriding AraC resistance in AML remains an unmet medical need. Here we show that the CHK1 inhibitor (CHK1i)...
3.
Smith A, Kulasekararaj A, Jiang J, Mian S, Mohamedali A, Gaken J, et al.
Lancet Haematol
. 2015 Dec;
2(5):e212-21.
PMID: 26688096
Background: A mechanism for clonal growth advantage in isolated del(5q) disease remains elusive. CSNK1A1 resides on the critically deleted region, and deletion of this gene has been shown in mouse...
4.
Kulasekararaj A, Jiang J, Smith A, Mohamedali A, Mian S, Gandhi S, et al.
Blood
. 2014 Aug;
124(17):2698-704.
PMID: 25139356
The distinction between acquired aplastic anemia (AA) and hypocellular myelodysplastic syndrome (hMDS) is often difficult, especially nonsevere AA. We postulated that somatic mutations are present in a subset of AA,...
5.
Mohamedali A, Alkhatabi H, Kulasekararaj A, Shinde S, Mian S, Malik F, et al.
Blood
. 2013 Jun;
122(4):567-70.
PMID: 23760614
Recent studies have shown that more than 80% of bone marrow (BM) samples from patients with myelodysplastic syndrome (MDS) harbor somatic mutations and/or genomic aberrations, which are of diagnostic and...
6.
Satoh T, Smith A, Sarde A, Lu H, Mian S, Mian S, et al.
PLoS One
. 2012 Apr;
7(4):e33891.
PMID: 22506009
Background: Langerhans cell histiocytosis (LCH) features inflammatory granuloma characterised by the presence of CD1a+ dendritic cells or 'LCH cells'. Badalian-Very et al. recently reported the presence of a canonical (V600E)B-RAF...