Swaine L Chen
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Explore the profile of Swaine L Chen including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Ambite I, Chao S, Rosenblad T, Hopkins R, Storm P, Ng Y, et al.
Life Sci Alliance
. 2025 Mar;
8(3).
PMID: 40036168
This study investigated the molecular basis of disease severity in acute pyelonephritis (APN), a common and potentially life-threatening bacterial infection. Two cohorts of infants with febrile urinary tract infection were...
2.
Lim Y, Ong K, Khor W, Chua F, Lim J, Tan L, et al.
Microorganisms
. 2024 Sep;
12(9).
PMID: 39338586
remains a significant foodborne pathogen globally with . Typhimurium presenting as a frequently occurring serovar. This study aimed to characterize 67 . Typhimurium isolates from humans, food, farms, and slaughterhouses...
3.
Yuan Q, Li W, Goh S, Chen S, Ng O, He Y, et al.
J Hazard Mater
. 2024 Sep;
479:135707.
PMID: 39236533
This study investigates the genetic traits and transmission mechanisms of cephalosporin-resistant Escherichia coli in tropical aquatic environments in Singapore. From 2016 to 2020, monthly samples were collected from wastewater treatment...
4.
Crestani C, Forde T, Bell J, Lycett S, Oliveira L, Pinto T, et al.
PLoS Pathog
. 2024 Aug;
20(8):e1012400.
PMID: 39133742
Group B Streptococcus (GBS) is a major human and animal pathogen that threatens public health and food security. Spill-over and spill-back between host species is possible due to adaptation and...
5.
Colomer-Winter C, Yong A, Chong K, Veleba M, Choo P, Gao I, et al.
PLoS Genet
. 2024 Aug;
20(8):e1011071.
PMID: 39102428
Sortase-assembled pili contribute to virulence in many Gram-positive bacteria. In Enterococcus faecalis, the endocarditis and biofilm-associated pilus (Ebp) is polymerized on the membrane by sortase C (SrtC) and attached to...
6.
Chen S, Tiruvayipati S, Tang W, M S Barkham T
Microbiol Spectr
. 2024 Jul;
12(9):e0053724.
PMID: 39052441
The (transketolase) gene is one of the seven gene fragments used in the multilocus sequence typing (MLST) system for . We discovered that the tkt_134 allele is derived from a...
7.
Tan C, Chong K, Yeong D, Ng C, Ismail M, Yap Z, et al.
mBio
. 2023 Dec;
15(1):e0238423.
PMID: 38078746
Although is a common wound pathogen, its pathogenic mechanisms during wound infection are unexplored. Here, combining a mouse wound infection model with transposon and RNA sequencing approaches, we identified the...
8.
Tan H, Lall A, Keppo J, Chen S
J Glob Antimicrob Resist
. 2023 Apr;
33:368-375.
PMID: 37019210
Objectives: Systemic strategies for combating antimicrobial resistance (AMR) currently focus on limiting antibiotic use and have been generally insufficient in preventing the rise of AMR. Additionally, they often generate other...
9.
Rashid R, Nair Z, Chia D, Chong K, Gassiot A, Morley S, et al.
mBio
. 2023 Jan;
14(1):e0307322.
PMID: 36629455
The bacterial cell membrane is an interface for cell envelope synthesis, protein secretion, virulence factor assembly, and a target for host cationic antimicrobial peptides (CAMPs). To resist CAMP killing, several...
10.
Luangraj M, Hiestand J, Rasphone O, Chen S, Davong V, Barkham T, et al.
Wellcome Open Res
. 2022 Dec;
7:148.
PMID: 36324702
is a normal commensal of the human gastro-intestinal and female genital tracts. It causes serious disease in neonates and pregnant women, as well as non-pregnant adults. Food-borne outbreaks have also...