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Svetlana Postnova

Explore the profile of Svetlana Postnova including associated specialties, affiliations and a list of published articles. Areas
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Articles 32
Citations 225
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Recent Articles
21.
Postnova S, Lockley S, Robinson P
J Biol Rhythms . 2018 Apr; 33(2):203-218. PMID: 29671707
A model of arousal dynamics is applied to predict objective performance and subjective sleepiness measures, including lapses and reaction time on a visual Performance Vigilance Test (vPVT), performance on a...
22.
Abeysuriya R, Lockley S, Robinson P, Postnova S
J Pineal Res . 2018 Feb; 64(4):e12474. PMID: 29437238
A biophysical model of the key aspects of melatonin synthesis and excretion has been developed, which is able to predict experimental dynamics of melatonin in plasma and saliva, and of...
23.
Postnova S, Lockley S, Robinson P
J Biol Rhythms . 2016 Jul; 31(5):498-508. PMID: 27432116
An improvement to our current quantitative model of arousal state dynamics is presented that more accurately predicts sleep propensity as measured with sleep dynamics depending on circadian phase and prior...
24.
Miller C, Kyle S, Gordon C, Espie C, Grunstein R, Mullins A, et al.
PLoS One . 2015 Dec; 10(12):e0145317. PMID: 26683607
Objectives: The aim of this preliminary study was to evaluate if Sleep Restriction Therapy for insomnia is associated with modifications to physiological arousal, indexed through overnight measures of plasma cortisol...
25.
Fulcher B, Phillips A, Postnova S, Robinson P
PLoS One . 2014 Mar; 9(3):e91982. PMID: 24651580
The orexinergic neurons of the lateral hypothalamus (Orx) are essential for regulating sleep-wake dynamics, and their loss causes narcolepsy, a disorder characterized by severe instability of sleep and wake states....
26.
Postnova S, Postnov D, Seneviratne M, Robinson P
J Biol Rhythms . 2014 Feb; 29(1):60-70. PMID: 24492883
A physiologically based mathematical model of sleep-wake cycles is used to examine the effects of shift rotation interval (RI) (i.e., the number of days spent on each shift) on sleepiness...
27.
Tchaptchet A, Postnova S, Finke C, Schneider H, Huber M, Braun H
Brain Res . 2013 Aug; 1536:159-67. PMID: 23911648
A mechanism-based, Hodgkin-Huxley-type modeling approach is proposed that allows connecting the key parameters of experimental voltage-/patch-clamp data directly to the major control values of the model. The objective of this...
28.
Postnova S, Robinson P, Postnov D
PLoS One . 2013 Jan; 8(1):e53379. PMID: 23308206
Shift work has become an integral part of our life with almost 20% of the population being involved in different shift schedules in developed countries. However, the atypical work times,...
29.
Patriarca M, Postnova S, Braun H, Hernandez-Garcia E, Toral R
PLoS Comput Biol . 2012 Aug; 8(8):e1002650. PMID: 22927806
Recent advances in sleep neurobiology have allowed development of physiologically based mathematical models of sleep regulation that account for the neuronal dynamics responsible for the regulation of sleep-wake cycles and...
30.
Postnova S, Layden A, Robinson P, Phillips A, Abeysuriya R
J Biol Rhythms . 2012 Feb; 27(1):91-102. PMID: 22306977
The effects of permanent shift work on entrainment and sleepiness are examined using a mathematical model that combines a model of sleep-wake switch in the brain with a model of...