Svenja de Buhr
Overview
Explore the profile of Svenja de Buhr including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
66
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0
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Recent Articles
1.
de Buhr S, Grater F
Elife
. 2023 Oct;
12.
PMID: 37843155
c-Abl kinase, a key signaling hub in many biological processes ranging from cell development to proliferation, is tightly regulated by two inhibitory Src homology domains. An N-terminal myristoyl modification can...
2.
Ehret T, Heissenberg T, de Buhr S, Aponte-Santamaria C, Steinem C, Grater F
Biophys J
. 2023 Feb;
122(7):1325-1333.
PMID: 36814382
The four-point-one ezrin-radixin-moesin homology (FERM) protein domain is a multifunctional protein-lipid binding site, constituting an integral part of numerous membrane-associated proteins. Its interaction with the lipid phosphatidylinositol-4,5-bisphosphate (PIP), located at...
3.
Daday C, de Buhr S, Mercadante D, Grater F
Biophys J
. 2022 Feb;
121(5):684-691.
PMID: 35120901
Cellular mechanosensing is pivotal for virtually all biological processes, and many molecular mechano-sensors and their way of function are being uncovered. In this work, we suggest that c-Src kinase acts...
4.
Banterle N, Nievergelt A, de Buhr S, Hatzopoulos G, Brillard C, Andany S, et al.
Nat Commun
. 2021 Oct;
12(1):6180.
PMID: 34702818
Discovering mechanisms governing organelle assembly is a fundamental pursuit in biology. The centriole is an evolutionarily conserved organelle with a signature 9-fold symmetrical chiral arrangement of microtubules imparted onto the...
5.
Acebron I, Righetto R, Schoenherr C, de Buhr S, Redondo P, Culley J, et al.
EMBO J
. 2020 Aug;
39(19):e104743.
PMID: 32779739
Focal adhesion kinase (FAK) is a key component of the membrane proximal signaling layer in focal adhesion complexes, regulating important cellular processes, including cell migration, proliferation, and survival. In the...
6.
Brings S, Fleming T, de Buhr S, Beijer B, Lindner T, Wischnjow A, et al.
Biochim Biophys Acta Mol Basis Dis
. 2016 Dec;
1863(3):654-662.
PMID: 27932057
The reactive metabolite methylglyoxal (MG) has been identified as mediator of pain. Scavenging of free MG and the prevention of MG-derived post-translational modifications may provide a useful therapeutic treatment. An...