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Sven Hendrix

Explore the profile of Sven Hendrix including associated specialties, affiliations and a list of published articles. Areas
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Articles 69
Citations 1420
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Recent Articles
1.
Scheijen E, Veeningen N, Duwe S, Ivanova A, Van Broeckhoven J, Hendrix S, et al.
J Biomed Sci . 2025 Jan; 32(1):12. PMID: 39844195
Background: Deficient DNA repair and excessive DNA damage contribute to neurodegenerative disease. However, the role of DNA damage and repair in spinal cord injury (SCI) is unclear. SCI, a debilitating...
2.
Slaets H, Veeningen N, de Keizer P, Hellings N, Hendrix S
Aging Cell . 2024 Aug; 23(10):e14300. PMID: 39113243
Loss of proper T-cell functioning is a feature of aging that increases the risk of developing chronic diseases. In aged individuals, highly differentiated T cells arise with a reduced expression...
3.
Schepers M, Hendrix S, Mussen F, Van Breedam E, Ponsaerts P, Lemmens S, et al.
Neurotherapeutics . 2024 May; 21(4):e00372. PMID: 38760316
Spinal cord injury (SCI) is a life-changing event that severely impacts the patient's quality of life. Modulating neuroinflammation, which exacerbates the primary injury, and stimulating neuro-regenerative repair mechanisms are key...
4.
Hamad I, Van Broeckhoven J, Cardilli A, Hellings N, Strowig T, Lemmens S, et al.
Nutrients . 2023 Oct; 15(19). PMID: 37836468
In recent years, the gut-central nervous system axis has emerged as a key factor in the pathophysiology of spinal cord injury (SCI). Interleukin-13 (IL-13) has been shown to have anti-inflammatory...
5.
Vangansewinkel T, Lemmens S, Tiane A, Geurts N, Dooley D, Vanmierlo T, et al.
FASEB J . 2023 May; 37(6):e22939. PMID: 37130013
Traumatic spinal cord injury (SCI) most often leads to permanent paralysis due to the inability of axons to regenerate in the adult mammalian central nervous system (CNS). In the past,...
6.
Erens C, Van Broeckhoven J, Bronckaers A, Lemmens S, Hendrix S
J Neurotrauma . 2022 Dec; 40(9-10):820-832. PMID: 36503258
L-arginine is a semi-essential amino acid involved in a variety of physiological processes in the central nervous system (CNS). It is essential in the survival and functionality of neuronal cells....
7.
Scheijen E, Hendrix S, Wilson 3rd D
Antioxidants (Basel) . 2022 Sep; 11(9). PMID: 36139802
Oxidative stress occurs at various phases of spinal cord injury (SCI), promoting detrimental processes such as free radical injury of proteins, nucleic acids, lipids, cytoskeleton, and organelles. Oxidative DNA damage...
8.
Van Broeckhoven J, Erens C, Sommer D, Scheijen E, Sanchez S, Vidal P, et al.
J Neuroinflammation . 2022 Apr; 19(1):102. PMID: 35488301
Background: Spinal cord injury (SCI) elicits a robust neuroinflammatory reaction which, in turn, exacerbates the initial mechanical damage. Pivotal players orchestrating this response are macrophages (Mφs) and microglia. After SCI,...
9.
Kemps H, Dessy C, Dumas L, Sonveaux P, Alders L, Van Broeckhoven J, et al.
J Cereb Blood Flow Metab . 2022 Feb; 42(6):979-996. PMID: 35209740
Extremely low frequency electromagnetic stimulation (ELF-EMS) has been considered as a neuroprotective therapy for ischemic stroke based on its capacity to induce nitric oxide (NO) signaling. Here, we examined whether...
10.
Erens C, Van Broeckhoven J, Hoeks C, Schabbauer G, Cheng P, Chen L, et al.
Biomedicines . 2022 Feb; 10(2). PMID: 35203413
Background: Spinal cord injury (SCI) elicits robust neuroinflammation that eventually exacerbates the initial damage to the spinal cord. L-arginine is critical for the responsiveness of T cells, which are important...