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Suzanne Scott

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Articles 51
Citations 1567
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Recent Articles
1.
Westhaus A, Barba-Sarasua E, Chen Y, Hsu K, Scott S, Knight M, et al.
Mol Ther . 2024 Dec; PMID: 39673125
Chimeric antigen receptor (CAR) T cell (CAR-T) therapies present options for patients diagnosed with certain leukemias. Recent advances of the technology included a method to integrate the CAR into the...
2.
Scott S, Westhaus A, Nazareth D, Cabanes-Creus M, Navarro R, Chandra D, et al.
Mol Ther Methods Clin Dev . 2024 Nov; 32(4):101351. PMID: 39498467
Gene therapies using recombinant adeno-associated virus (AAV) vectors have demonstrated considerable clinical success in the treatment of genetic disorders. Improved vectors with favorable tropism profiles, decreased immunogenicity, and enhanced manufacturability...
3.
Drouyer M, Merjane J, Nedelkoska T, Westhaus A, Scott S, Lee S, et al.
Mol Ther Nucleic Acids . 2024 Aug; 35(3):102264. PMID: 39108635
Viral vectors based on recombinant adeno-associated virus (rAAV) have become the most widely used system for therapeutic gene delivery in the central nervous system (CNS). Despite clinical safety and efficacy...
4.
Kelley Jones C, Scott S, Pashayan N, Morris S, Okan Y, Waller J
Med Decis Making . 2024 Jun; 44(5):586-600. PMID: 38828503
Background: A risk-stratified breast screening program could offer low-risk women less screening than is currently offered by the National Health Service. The acceptability of this approach may be enhanced if...
5.
Drouyer M, Chu T, Labit E, Haase F, Navarro R, Nazareth D, et al.
Mol Ther Methods Clin Dev . 2024 Apr; 32(2):101234. PMID: 38558569
Gene therapies and associated technologies are transforming biomedical research and enabling novel therapeutic options for patients living with debilitating and incurable genetic disorders. The vector system based on recombinant adeno-associated...
6.
Drouyer M, Merjane J, Nazareth D, Knight M, Scott S, Liao S, et al.
Mol Ther . 2024 Feb; 32(3):818-836. PMID: 38297833
Directed evolution of natural AAV9 using peptide display libraries have been widely used in the search for an optimal recombinant AAV (rAAV) for transgene delivery across the blood-brain barrier (BBB)...
7.
Saeterbakken A, Stien N, Pedersen H, Langer K, Scott S, Michailov M, et al.
Sports Med Open . 2024 Jan; 10(1):10. PMID: 38240903
Background: Climbing is an intricate sport composed of various disciplines, holds, styles, distances between holds, and levels of difficulty. In highly skilled climbers the potential for further strength-specific adaptations to...
8.
Kok C, Tsurusaki S, Cabanes-Creus M, Igoor S, Rao R, Skelton R, et al.
Mol Ther Methods Clin Dev . 2023 Sep; 30:459-473. PMID: 37674904
Recombinant adeno-associated viruses (rAAVs) have emerged as one of the most promising gene therapy vectors that have been successfully used in pre-clinical models of heart disease. However, this has not...
9.
OToole S, Moazzez R, Wojewodka G, Zeki S, Jafari J, Hope K, et al.
BMJ Open . 2023 Aug; 13(8):e076661. PMID: 37620257
Introduction: Just under half of patients with obstructive sleep apnoea (OSA) also have gastro-oesophageal reflux disease (GORD). These conditions appear to be inter-related and continual positive airway pressure (CPAP) therapy,...
10.
Jones D, Ali O, Honey S, Surr C, Scott S, de Wit N, et al.
Br J Gen Pract . 2023 Jun; 73(733):e597-e604. PMID: 37365009
Background: Cancer is predominantly a disease of older adults. To date there has been little research on the experiences of older adults or their views on the diagnostic pathway. Aim:...