Suzanne E Neumueller
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Explore the profile of Suzanne E Neumueller including associated specialties, affiliations and a list of published articles.
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12
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57
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Recent Articles
1.
Neumueller S, Buiter N, Hilbert G, Grams K, Taylor R, Desalvo J, et al.
Front Physiol
. 2023 Oct;
14:1277601.
PMID: 37885800
Synthetic opioids like fentanyl have improved the standard of care for many patients in the clinical setting, but their abuse leads to tens of thousands of overdose deaths annually. The...
2.
Grams K, Neumueller S, Mouradian Jr G, Burgraff N, Hodges M, Pan L, et al.
Physiol Genomics
. 2023 Aug;
55(11):487-503.
PMID: 37602394
Chronic hypercapnia (CH) is a hallmark of respiratory-related diseases, and the level of hypercapnia can acutely or progressively become more severe. Previously, we have shown time-dependent adaptations in steady-state physiology...
3.
Buchholz K, Neumueller S, Burgraff N, Hodges M, Pan L, Forster H
J Appl Physiol (1985)
. 2022 Sep;
133(5):1106-1118.
PMID: 36135953
Chronic hypercapnia (CH) is a hallmark of chronic lung disease, and CH increases the risk for acute-on-chronic exacerbations leading to greater hypoxemia/hypercapnia and poor health outcomes. However, the role of...
4.
Buchholz K, Burgraff N, Neumueller S, Hodges M, Pan L, Forster H
J Appl Physiol (1985)
. 2021 Feb;
130(4):1259-1273.
PMID: 33539265
Chronic hypercapnia (CH) is a hallmark of respiratory diseases such as chronic obstructive pulmonary disease. In such patients, mechanical ventilation is often used to restore normal blood-gas homeostasis. However, little...
5.
Burgraff N, Neumueller S, Buchholz K, LeClaire J, Hodges M, Pan L, et al.
FASEB J
. 2019 Nov;
33(12):14491-14505.
PMID: 31670983
Despite the prevalence of CO retention in human disease, little is known about the adaptive neurobiological effects of chronic hypercapnia. We have recently shown 30-d exposure to increased inspired CO...
6.
Midbrain and cerebral inflammatory and glutamatergic adaptations during chronic hypercapnia in goats
Burgraff N, Neumueller S, Buchholz K, Hodges M, Pan L, Forster H
Brain Res
. 2019 Sep;
1724:146437.
PMID: 31494104
Cognitive impairment is associated with multiple human diseases that have in common chronic hypercapnia. However, the mechanisms leading to chronic hypercapnia-induced cognitive decline are not known. We have previously shown...
7.
Glutamate receptor plasticity in brainstem respiratory nuclei following chronic hypercapnia in goats
Burgraff N, Neumueller S, Buchholz K, Hodges M, Pan L, Forster H
Physiol Rep
. 2019 Apr;
7(8):e14035.
PMID: 30993898
Patients that retain CO in respiratory diseases such as chronic obstructive pulmonary disease (COPD) have worse prognoses and higher mortality rates than those with equal impairment of lung function without...
8.
Burgraff N, Neumueller S, Buchholz K, Langer 3rd T, Hodges M, Pan L, et al.
J Physiol
. 2018 Sep;
596(22):5343-5363.
PMID: 30211447
Key Points: Chronic hypercapnia per se has distinct effects on the mechanisms regulating steady-state ventilation and the CO /H chemoreflex. Chronic hypercapnia leads to sustained hyperpnoea that exceeds predicted ventilation...
9.
Langer 3rd T, Neumueller S, Crumley E, Burgraff N, Talwar S, Hodges M, et al.
J Appl Physiol (1985)
. 2017 Aug;
123(6):1532-1544.
PMID: 28839004
Neuromodulator interdependence posits that changes in one or more neuromodulators are compensated by changes in other modulators to maintain stability in the respiratory control network. Herein, we studied compensatory neuromodulation...
10.
Langer 3rd T, Neumueller S, Crumley E, Burgraff N, Talwar S, Hodges M, et al.
Respir Physiol Neurobiol
. 2017 Feb;
239:10-25.
PMID: 28137700
Pulmonary ventilation (V̇) in awake and sleeping goats does not change when antagonists to several excitatory G protein-coupled receptors are dialyzed unilaterally into the ventral respiratory column (VRC). Concomitant changes...