Sushmita Negi
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Explore the profile of Sushmita Negi including associated specialties, affiliations and a list of published articles.
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13
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37
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Recent Articles
1.
Devi S, Negi S, Tandel N, Dalai S, Tyagi R
Drug Discov Today
. 2024 Nov;
30(1):104254.
PMID: 39608487
Oleuropein (OLP) holds promise as a therapeutic candidate for both Plasmodium falciparum infection and cancer. It modulates the phosphoinositide 3-kinase (PI3K)-Akt1 signaling pathway to regulate inflammation and restore immune homeostasis....
2.
Tiwari S, Kumar R, Devi S, Sharma P, Chaudhary N, Negi S, et al.
Discov Nano
. 2024 Oct;
19(1):173.
PMID: 39472386
No abstract available.
3.
Khajuria A, Alajangi H, Sharma A, Kaur H, Sharma P, Negi S, et al.
Discov Nano
. 2024 Sep;
19(1):145.
PMID: 39256285
Breast cancer is one of the leading causes of death among women globally, making its diagnosis and treatment challenging. The use of nanotechnology for cancer diagnosis and treatment is an...
4.
Sharma P, Chaudhary N, Devi S, Negi S, Tandel N, Tyagi R
Front Microbiol
. 2024 Sep;
15:1453998.
PMID: 39228384
Drug resistance in presents a formidable challenge to the humanity. And, unavailability of an effective vaccine worsens the situation further. Autophagy is one of the mechanisms employed by parasite to...
5.
Tiwari S, Kumar R, Devi S, Sharma P, Chaudhary N, Negi S, et al.
Discov Nano
. 2024 Aug;
19(1):136.
PMID: 39217276
The suboptimal efficacies of existing anti-malarial drugs attributed to the emergence of drug resistance dampen the clinical outcomes. Hence, there is a need for developing novel drug and drug targets....
6.
Devi S, Negi S, Sharma P, Tandel N, Tyagi R
STAR Protoc
. 2024 Jun;
5(3):103141.
PMID: 38905105
The anti-inflammatory activity of a phytocompound (oleuropein [OLP]) in the lipopolysaccharide (LPS)-mimicked macrophage model of inflammation demonstrates the importance of PI3K-Akt1 signaling in establishing "immune homeostasis." Here, we present a...
7.
Sharma P, Tandel N, Kumar R, Negi S, Sharma P, Devi S, et al.
iScience
. 2024 Apr;
27(4):109463.
PMID: 38562521
Antimalarial drug resistance and unavailability of effective vaccine warrant for newer drugs and drug targets. Hence, anti-inflammatory activity of phyto-compound (oleuropein; OLP) was determined in antigen (LPS)-stimulated human THP-1 macrophages...
8.
Negi S, Tandel N, Garg N, Sharma P, Kumar R, Sharma P, et al.
Int J Nanomedicine
. 2024 Mar;
19:2149-2177.
PMID: 38482519
Background: Rheumatoid arthritis (RA) is a common acute inflammatory autoimmune connective tissue arthropathy. The genetic studies, tissue analyses, experimental animal models, and clinical investigations have confirmed that stromal tissue damage...
9.
Negi S, Tandel N, Sharma P, Kumar R, Tyagi R
Drug Discov Today
. 2023 Jun;
28(8):103671.
PMID: 37330038
Rheumatoid arthritis (RA) is an inflammatory, autoimmune and connective-tissue arthropathy. The methotrexate (MTX) and aceclofenac (ACL) combination drug regimen is known to regulate the immunological pathways. Also, RA-elicited inflammation is...
10.
Tandel N, Negi S, Dalai S, Tyagi R
Int Rev Immunol
. 2023 Feb;
42(4):304-322.
PMID: 36731424
The innate lymphoid cell (ILC) system comprising of the circulating and tissue-resident cells is known to clear infectious pathogens, establish immune homeostasis as well as confer antitumor immunity. Human natural...