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Rajeev K Tyagi

Explore the profile of Rajeev K Tyagi including associated specialties, affiliations and a list of published articles. Areas
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Articles 59
Citations 534
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Recent Articles
1.
Devi S, Negi S, Tandel N, Dalai S, Tyagi R
Drug Discov Today . 2024 Nov; 30(1):104254. PMID: 39608487
Oleuropein (OLP) holds promise as a therapeutic candidate for both Plasmodium falciparum infection and cancer. It modulates the phosphoinositide 3-kinase (PI3K)-Akt1 signaling pathway to regulate inflammation and restore immune homeostasis....
2.
Tiwari S, Kumar R, Devi S, Sharma P, Chaudhary N, Negi S, et al.
Discov Nano . 2024 Oct; 19(1):173. PMID: 39472386
No abstract available.
3.
Khajuria A, Alajangi H, Sharma A, Kaur H, Sharma P, Negi S, et al.
Discov Nano . 2024 Sep; 19(1):145. PMID: 39256285
Breast cancer is one of the leading causes of death among women globally, making its diagnosis and treatment challenging. The use of nanotechnology for cancer diagnosis and treatment is an...
4.
Sharma P, Chaudhary N, Devi S, Negi S, Tandel N, Tyagi R
Front Microbiol . 2024 Sep; 15:1453998. PMID: 39228384
Drug resistance in presents a formidable challenge to the humanity. And, unavailability of an effective vaccine worsens the situation further. Autophagy is one of the mechanisms employed by parasite to...
5.
Tiwari S, Kumar R, Devi S, Sharma P, Chaudhary N, Negi S, et al.
Discov Nano . 2024 Aug; 19(1):136. PMID: 39217276
The suboptimal efficacies of existing anti-malarial drugs attributed to the emergence of drug resistance dampen the clinical outcomes. Hence, there is a need for developing novel drug and drug targets....
6.
Mahalingam G, Tandel N, Tyagi R, Marepally S
Mol Ther Nucleic Acids . 2024 Aug; 35(3):102276. PMID: 39176176
No abstract available.
7.
Devi S, Negi S, Sharma P, Tandel N, Tyagi R
STAR Protoc . 2024 Jun; 5(3):103141. PMID: 38905105
The anti-inflammatory activity of a phytocompound (oleuropein [OLP]) in the lipopolysaccharide (LPS)-mimicked macrophage model of inflammation demonstrates the importance of PI3K-Akt1 signaling in establishing "immune homeostasis." Here, we present a...
8.
Sharma P, Tandel N, Kumar R, Negi S, Sharma P, Devi S, et al.
iScience . 2024 Apr; 27(4):109463. PMID: 38562521
Antimalarial drug resistance and unavailability of effective vaccine warrant for newer drugs and drug targets. Hence, anti-inflammatory activity of phyto-compound (oleuropein; OLP) was determined in antigen (LPS)-stimulated human THP-1 macrophages...
9.
Negi S, Tandel N, Garg N, Sharma P, Kumar R, Sharma P, et al.
Int J Nanomedicine . 2024 Mar; 19:2149-2177. PMID: 38482519
Background: Rheumatoid arthritis (RA) is a common acute inflammatory autoimmune connective tissue arthropathy. The genetic studies, tissue analyses, experimental animal models, and clinical investigations have confirmed that stromal tissue damage...
10.
Tandel N, Patel D, Thakkar M, Shah J, Tyagi R, Dalai S
Heliyon . 2024 Mar; 10(5):e26887. PMID: 38455541
Poly(I:C) and R848, synthetic ligands that activate Toll-like receptor 3 (TLR3) and TLR7/8 respectively, have been well-established for their ability to stimulate the immune system and induce antigen-specific immune responses....