Sushil Awal
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Explore the profile of Sushil Awal including associated specialties, affiliations and a list of published articles.
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7
Citations
89
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Recent Articles
1.
Amin P, Awal S, Vigneron S, Roque S, Mechali F, Labbe J, et al.
Oncogene
. 2021 Oct;
41(1):1-14.
PMID: 34686773
PP2A is a major serine/threonine phosphatase class involved in the regulation of cell signaling through the removal of protein phosphorylation. This class of phosphatases is comprised of different heterotrimeric complexes...
2.
Lupse B, Annamalai K, Ibrahim H, Kaur S, Geravandi S, Sarma B, et al.
Cell Rep
. 2021 Aug;
36(5):109490.
PMID: 34348155
Pancreatic β-cell failure is the key pathogenic element of the complex metabolic deterioration in type 2 diabetes (T2D); its underlying pathomechanism is still elusive. Here, we identify pleckstrin homology domain...
3.
Goguet-Rubio P, Amin P, Awal S, Vigneron S, Charrasse S, Mechali F, et al.
Biomolecules
. 2020 Dec;
10(11).
PMID: 33266510
Protein phosphorylation is a post-translational modification essential for the control of the activity of most enzymes in the cell. This protein modification results from a fine-tuned balance between kinases and...
4.
Ardestani A, Li S, Annamalai K, Lupse B, Geravandi S, Dobrowolski A, et al.
Nat Commun
. 2019 Nov;
10(1):5015.
PMID: 31676778
The loss of functional insulin-producing β-cells is a hallmark of diabetes. Mammalian sterile 20-like kinase 1 (MST1) is a key regulator of pancreatic β-cell death and dysfunction; its deficiency restores...
5.
Krupina K, Kleiss C, Awal S, Rodriguez-Hernandez I, Sanz-Moreno V, Sumara I
Mol Cell Oncol
. 2018 Mar;
5(2):e1271494.
PMID: 29487893
Defects in mitosis can lead to aneuploidy, which is a common feature of human cancers. Spindle Assembly Checkpoint (SAC) controls fidelity of chromosome segregation in mitosis to prevent aneuploidy. The...
6.
Yuan T, Rafizadeh S, Azizi Z, Lupse B, Gorrepati K, Awal S, et al.
JCI Insight
. 2016 Nov;
1(18):e86326.
PMID: 27812538
Loss of functional pancreatic β cells is a hallmark of both type 1 and 2 diabetes. Identifying the pathways that promote β cell proliferation and/or block β cell apoptosis is...
7.
Mordhorst T, Awal S, Jordan S, Petters C, Sartoris L, Dringen R, et al.
Mar Drugs
. 2015 Feb;
13(2):920-35.
PMID: 25679913
Based on the chemical structure and the known chemical synthesis of the marine sponge alkaloid ageladine A, we synthesized the ageladine A-derivative 4-(naphthalene-2-yl)-1H-imidazo[4,5-c]pyridine trifluoroacetate (LysoGlow84). The two-step synthesis started with...