Kanaka Durga Devi Gorrepati
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Explore the profile of Kanaka Durga Devi Gorrepati including associated specialties, affiliations and a list of published articles.
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7
Citations
109
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Recent Articles
1.
Yuan T, Annamalai K, Naik S, Lupse B, Geravandi S, Pal A, et al.
Nat Commun
. 2021 Aug;
12(1):4928.
PMID: 34389720
Diabetes results from a decline in functional pancreatic β-cells, but the molecular mechanisms underlying the pathological β-cell failure are poorly understood. Here we report that large-tumor suppressor 2 (LATS2), a...
2.
Lupse B, Annamalai K, Ibrahim H, Kaur S, Geravandi S, Sarma B, et al.
Cell Rep
. 2021 Aug;
36(5):109490.
PMID: 34348155
Pancreatic β-cell failure is the key pathogenic element of the complex metabolic deterioration in type 2 diabetes (T2D); its underlying pathomechanism is still elusive. Here, we identify pleckstrin homology domain...
3.
Gorrepati K, Lupse B, Annamalai K, Yuan T, Maedler K, Ardestani A
iScience
. 2018 Sep;
1:72-86.
PMID: 30227958
Impaired pancreatic β-cell survival contributes to the reduced β-cell mass in diabetes, but underlying regulatory mechanisms and key players in this process remain incompletely understood. Here, we identified the deubiquitinase...
4.
Gorrepati K, He W, Lupse B, Yuan T, Maedler K, Ardestani A
Int J Mol Sci
. 2018 Mar;
19(4).
PMID: 29587369
Loss of pancreatic β-cell function and/or mass is a central hallmark of all forms of diabetes but its molecular basis is incompletely understood. β-cell apoptosis contributes to the reduced β-cell...
5.
Yuan T, Rafizadeh S, Gorrepati K, Lupse B, Oberholzer J, Maedler K, et al.
Diabetologia
. 2016 Dec;
60(4):668-678.
PMID: 28004151
Aims/hypothesis: Mechanistic target of rapamycin complex 1 (mTORC1) is a master regulator of nutritional status at the cellular and organismic level. While mTORC1 mediates beta cell growth and expansion, its...
6.
Yuan T, Rafizadeh S, Azizi Z, Lupse B, Gorrepati K, Awal S, et al.
JCI Insight
. 2016 Nov;
1(18):e86326.
PMID: 27812538
Loss of functional pancreatic β cells is a hallmark of both type 1 and 2 diabetes. Identifying the pathways that promote β cell proliferation and/or block β cell apoptosis is...
7.
Kangwa M, Yelemane V, Polat A, Gorrepati K, Grasselli M, Fernandez-Lahore M
AMB Express
. 2015 Nov;
5(1):70.
PMID: 26556030
The major platform for high level recombinant protein production is based on genetically modified microorganisms like Escherichia coli (E. coli) due to its short dividing time, ability to use inexpensive...