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Susanne C van den Brink

Explore the profile of Susanne C van den Brink including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 1082
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Recent Articles
1.
Dijkhuis L, Johns A, Ragusa D, van den Brink S, Pina C
Emerg Top Life Sci . 2023 Dec; 7(4):439-454. PMID: 38095554
Haematopoietic stem cells (HSCs) are the most extensively studied adult stem cells. Yet, six decades after their first description, reproducible and translatable generation of HSC in vitro remains an unmet...
2.
Tessadori F, Tsingos E, Colizzi E, Kruse F, van den Brink S, van den Boogaard M, et al.
Elife . 2021 Aug; 10. PMID: 34372968
Organ laterality refers to the left-right asymmetry in disposition and conformation of internal organs and is established during embryogenesis. The heart is the first organ to display visible left-right asymmetries...
3.
van den Brink S, van Oudenaarden A
Trends Cell Biol . 2021 Jul; 31(9):747-759. PMID: 34304959
3D gastruloids, aggregates of embryonic stem cells that recapitulate key aspects of gastrula-stage embryos, have emerged as a powerful tool to study the early stages of mammalian post-implantation development in...
4.
Pereira Daoud A, Popovic M, Dondorp W, Trani Bustos M, Bredenoord A, Chuva de Sousa Lopes S, et al.
Hum Reprod Update . 2020 Jul; 26(6):779-798. PMID: 32712668
Background: Studying the human peri-implantation period remains hindered by the limited accessibility of the in vivo environment and scarcity of research material. As such, continuing efforts have been directed towards...
5.
Moris N, Anlas K, van den Brink S, Alemany A, Schroder J, Ghimire S, et al.
Nature . 2020 Jun; 582(7812):410-415. PMID: 32528178
The body plan of the mammalian embryo is shaped through the process of gastrulation, an early developmental event that transforms an isotropic group of cells into an ensemble of tissues...
6.
van den Brink S, Alemany A, van Batenburg V, Moris N, Blotenburg M, Vivie J, et al.
Nature . 2020 Mar; 579(7799):E11. PMID: 32132714
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
7.
van den Brink S, Alemany A, van Batenburg V, Moris N, Blotenburg M, Vivie J, et al.
Nature . 2020 Feb; 582(7812):405-409. PMID: 32076263
Gastruloids are three-dimensional aggregates of embryonic stem cells that display key features of mammalian development after implantation, including germ-layer specification and axial organization. To date, the expression pattern of only...
8.
van den Brink S, Sage F, Vertesy A, Spanjaard B, Peterson-Maduro J, Baron C, et al.
Nat Methods . 2017 Sep; 14(10):935-936. PMID: 28960196
No abstract available.
9.
van den Brink S, Baillie-Johnson P, Balayo T, Hadjantonakis A, Nowotschin S, Turner D, et al.
Development . 2014 Nov; 141(22):4231-42. PMID: 25371360
Mouse embryonic stem cells (mESCs) are clonal populations derived from preimplantation mouse embryos that can be propagated in vitro and, when placed into blastocysts, contribute to all tissues of the...