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Susan E Stuber

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Articles 13
Citations 344
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Recent Articles
1.
Nieves R, Latham T, Marte N, Berges Morales M, Sanchez L, Urcuyo G, et al.
Blood Adv . 2025 Jan; PMID: 39820633
Sickle cell anemia (SCA) is recognized globally, but little is known about affected Hispanic populations. In partnership with Dominican Republic, a Hispanic Caribbean Island with a large SCA population, a...
2.
Dei-Adomakoh Y, Segbefia C, Latham T, Lane A, Dzefi-Tettey K, Amissah-Arthur K, et al.
NEJM Evid . 2024 Dec; 4(2):EVIDoa2400402. PMID: 39647172
Background: Hemoglobin SC (HbSC) is a common sickle hemoglobinopathy that causes acute complications, chronic organ damage, and early death with no established disease-modifying treatment. In this trial, we examined the...
3.
Segbefia C, Smart L, Stuber S, Amissah-Arthur K, Dzefi-Tettey K, Ekpale P, et al.
Br J Haematol . 2024 Oct; 205(6):2470-2480. PMID: 39406687
HbSC disease is a common form of sickle cell disease with significant morbidity and early mortality. Whether hydroxyurea is beneficial for HbSC disease is unknown. Prospective Identification of Variables as...
4.
Power-Hays A, Namazzi R, Kato C, McElhinney K, Conroy A, Hume H, et al.
Acta Haematol . 2024 Jun; :1-12. PMID: 38824918
Introduction: People with sickle cell anemia (SCA) may require frequent blood transfusions to treat acute and chronic complications. Hydroxyurea is a life-saving treatment for SCA that could also decrease the...
5.
Aygun B, Lane A, Smart L, Santos B, Tshilolo L, Williams T, et al.
Lancet Haematol . 2024 May; 11(6):e425-e435. PMID: 38701812
Background: Realizing Effectiveness Across Continents with Hydroxyurea (REACH) is an open-label non-randomised trial of hydroxyurea (hydroxycarbamide) in children with sickle cell anaemia in sub-Saharan Africa. The short-term results of REACH...
6.
Power-Hays A, Tomlinson G, Tshilolo L, Santos B, Williams T, Olupot-Olupot P, et al.
Am J Hematol . 2024 Feb; 99(4):625-632. PMID: 38332651
Children with sickle cell anemia (SCA) in Africa frequently require transfusions for SCA complications. Despite limited blood supplies, strategies to reduce their transfusion needs have not been widely evaluated or...
7.
Smart L, Segbefia C, Latham T, Stuber S, Amissah-Arthur K, Dzefi-Tettey K, et al.
Trials . 2023 Sep; 24(1):603. PMID: 37737189
Background: Haemoglobin SC (HbSC) is a common form of sickle cell disease (SCD), especially among individuals of West African ancestry. Persons with HbSC disease suffer from the same clinical complications...
8.
Ambrose E, Latham T, Songoro P, Charles M, Lane A, Stuber S, et al.
Lancet Haematol . 2023 Mar; 10(4):e261-e271. PMID: 36870358
Background: Transcranial Doppler screening with chronic transfusions reduces stroke risk in children with sickle cell anaemia but is not feasible in low-resource settings. Hydroxyurea is an alternative treatment to decrease...
9.
Olupot-Olupot P, Tomlinson G, Williams T, Tshilolo L, Santos B, Smart L, et al.
Blood . 2022 Nov; 141(12):1402-1410. PMID: 36375125
Realizing Effectiveness Across Continents with Hydroxyurea (REACH, NCT01966731) provides hydroxyurea at maximum tolerated dose (MTD) for children with sickle cell anemia (SCA) in sub-Saharan Africa. Beyond reducing SCA-related clinical events,...
10.
Smart L, Ambrose E, Balyorugulu G, Songoro P, Shabani I, Komba P, et al.
Acta Haematol . 2022 Aug; 146(2):95-105. PMID: 35977532
Introduction: Stroke is a severe complication of sickle cell anemia (SCA), with devastating sequelae. Transcranial Doppler (TCD) ultrasonography predicts stroke risk, but implementing TCD screening with suitable treatment for primary...