Thomas N Williams
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Explore the profile of Thomas N Williams including associated specialties, affiliations and a list of published articles.
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249
Citations
12372
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Recent Articles
1.
Ayuen D, Olupot-Olupot P, Muhindo R, Onyamboko M, Ajayi S, Chimjinda N, et al.
Malar J
. 2025 Mar;
24(1):77.
PMID: 40069748
Background: Anaemia is a deleterious consequence of malaria, and its accurate diagnosis is crucial for effective management. However, laboratory methods for measuring haemoglobin (Hb) concentration, like the Coulter Counter and...
2.
3.
Scourfield L, Nardo-Marino A, Williams T, Rees D
Haematologica
. 2024 Nov;
110(3):546-561.
PMID: 39568431
Sickle cell disease (SCD) is one of the commonest severe inherited disorders in the world. Infection accounts for a significant amount of the morbidity and mortality, particularly in sub-Saharan Africa,...
4.
Connon R, Olupot-Olupot P, Pistorius A, Okiror W, Ssenyondo T, Muhindo R, et al.
BMC Med
. 2024 Nov;
22(1):516.
PMID: 39506794
Background: African children with severe malaria are at increased risk of non-typhoidal salmonellae co-infection. Broad-spectrum antibiotics are recommended by guidelines but the optimal class and dose have not been established....
5.
Maitland K, Hamaluba M, Obonyo N, Oguda E, Mogoka C, Williams T, et al.
Wellcome Open Res
. 2024 Sep;
8:484.
PMID: 39219856
Background: Even on the best antimalarial treatments (injectable artesunate) African children with severe malaria have poor outcomes with most deaths occurring early in the course of hospital admission (<24hours). Lactic...
6.
Maitland K, Obonyo N, Hamaluba M, Ogoda E, Mogaka C, Williams T, et al.
Wellcome Open Res
. 2024 Aug;
9:281.
PMID: 39184127
Background: African children with cerebral malaria and seizures caused are at greater risk of poor outcomes including death and neurological sequelae. The agonal events are severe hypoventilation and respiratory arrest...
7.
Kariuki S, Gilchrist J, Uyoga S, Macharia A, Makale J, Rayner J, et al.
J Infect Dis
. 2024 Jul;
231(1):e10-e16.
PMID: 38979599
Background: The Dantu blood group variant protects against Plasmodium falciparum infections, but its wider consequences have not been previously explored. Here, we investigate the impact of Dantu on susceptibility to...
8.
Kiguli S, Olupot-Olupot P, Hamaluba M, Giallongo E, Thomas K, Alaroker F, et al.
EClinicalMedicine
. 2024 May;
72:102640.
PMID: 38774673
Background: Severe pneumonia in African children results in poor long-term outcomes (deaths/readmissions) with undernutrition as a key risk factor. We hypothesised additional energy/protein-rich Ready-to-Use Therapeutic Foods (RUTF) would meet additional...
9.
Aygun B, Lane A, Smart L, Santos B, Tshilolo L, Williams T, et al.
Lancet Haematol
. 2024 May;
11(6):e425-e435.
PMID: 38701812
Background: Realizing Effectiveness Across Continents with Hydroxyurea (REACH) is an open-label non-randomised trial of hydroxyurea (hydroxycarbamide) in children with sickle cell anaemia in sub-Saharan Africa. The short-term results of REACH...
10.
Power-Hays A, Tomlinson G, Tshilolo L, Santos B, Williams T, Olupot-Olupot P, et al.
Am J Hematol
. 2024 Feb;
99(4):625-632.
PMID: 38332651
Children with sickle cell anemia (SCA) in Africa frequently require transfusions for SCA complications. Despite limited blood supplies, strategies to reduce their transfusion needs have not been widely evaluated or...