Suresh de Silva
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Explore the profile of Suresh de Silva including associated specialties, affiliations and a list of published articles.
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Articles
34
Citations
679
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Recent Articles
1.
Shuptrine C, Chen Y, Miriyala J, Lenz K, Moffett D, Nguyen T, et al.
Cancer Res
. 2024 Feb;
84(10):1550-1559.
PMID: 38381555
Significance: Lipid nanoparticle-encapsulated mRNA can efficiently encode complex fusion proteins encompassing immune checkpoint blockers and costimulators that functionally oligomerize in vivo with extended pharmacokinetics and durable exposure to induce potent...
2.
Wang C, Lai A, Baiu D, Smith K, Odorico J, Wilson K, et al.
J Immunol
. 2023 Nov;
212(2):284-294.
PMID: 37991420
There is considerable interest in therapeutically engaging human γδ T cells. However, due to the unique TCRs of human γδ T cells, studies from animal models have provided limited directly...
3.
Fromm G, de Silva S, Schreiber T
Front Immunol
. 2023 Oct;
14:1236332.
PMID: 37795079
The extracellular domain of tumor necrosis factor receptors (TNFR) generally require assembly into a homotrimeric quaternary structure as a prerequisite for initiation of signaling via the cytoplasmic domains. TNF receptor...
4.
Lai A, Patel A, Brewer F, Evans K, Johannes K, Gonzalez L, et al.
J Immunol
. 2022 Sep;
209(8):1475-1480.
PMID: 36096643
Vγ9Vδ2 T cell-targeted immunotherapy is of interest to harness its MHC-independent cytotoxic potential against a variety of cancers. Recent studies have identified heterodimeric butyrophilin (BTN) 2A1 and BTN3A1 as the...
5.
de Silva S, Lockhart K, Aslan P, Nash P, Hutton A, Malouf D, et al.
BMC Urol
. 2022 Sep;
22(1):141.
PMID: 36057604
Purpose: To develop a system for multi-parametric MRI to differentiate benign from malignant solid renal masses and assess its accuracy compared to the gold standard of histopathological diagnosis. Methods: This...
6.
Yoo K, Johannes K, Gonzalez L, Patel A, Shuptrine C, Opheim Z, et al.
J Immunol
. 2022 Jul;
209(3):510-525.
PMID: 35817517
Coinhibition of TIGIT (T cell immunoreceptor with Ig and ITIM domains) and PD-1/PD-L1 (PD-1/L1) may improve response rates compared with monotherapy PD-1/L1 blockade in checkpoint naive non-small cell lung cancer...
7.
de Souza P, Aslan P, Clark W, Nour R, de Silva S
Clin Genitourin Cancer
. 2022 Jun;
20(5):442-451.
PMID: 35710899
Introduction: Selective internal radiation therapy (SIRT) is a potential treatment of primary renal cell carcinoma (RCC) deemed unsuitable for conventional therapy. RESIRT is the first-in-human study to evaluate safety and...
8.
Katelaris A, de Silva S, Thompson D
Urol Case Rep
. 2021 Nov;
40:101906.
PMID: 34754753
Conventional staging for bladder cancer involves CT and TURBT, and is thought to understage up to fifty-percent of T1 tumours. This report details the case of a 64-year-old male who...
9.
de Silva S, Lockhart K, Aslan P, Nash P, Hutton A, Malouf D, et al.
BMC Urol
. 2021 Apr;
21(1):67.
PMID: 33888122
Background: MRI is playing an increasing role in risk stratification and non-invasive diagnosis of the undifferentiated small renal mass. This study was designed to assess the reliability of MRI in...
10.
de Silva S, Lockhart K, Aslan P, Nash P, Hutton A, Malouf D, et al.
J Med Imaging Radiat Oncol
. 2020 Aug;
64(6):762-768.
PMID: 32743914
Introduction: The aim of this study was to assess the qualitative and MRI findings of renal tumours, to determine which lesions contain microscopic fat, one of the potential differentiating factors...